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Risk of primary infection and reinfection with respiratory syncytial virus.
Respiratory syncytial virus is the most important cause of serious lower respiratory tract infection in children. For children followed up from birth in the Houston Family Study, the infection rateExpand
Emerging infections: pandemic influenza.
This challenge provides an opportunity to develop, test, and have in place a strategy for control of interpandemic influenza before the next pandemic. Expand
The Japanese experience with vaccinating schoolchildren against influenza.
The effect of influenza on mortality is much greater in Japan than in the United States and can be measured about equally well in terms of deaths from all causes and deaths attributed to pneumonia or influenza. Expand
Effectiveness of live, attenuated intranasal influenza virus vaccine in healthy, working adults: a randomized controlled trial.
Intranasal trivalent LAIV vaccine was safe and effective in healthy, working adults in a year in which a drifted influenza A virus predominated, suggesting that LAIV provided substantial cross-protection against this variant influenza Airus strain. Expand
Impact of respiratory virus infections on persons with chronic underlying conditions.
It is suggested that respiratory virus infections commonly trigger serious acute respiratory conditions that result in hospitalization of patients with chronic underlying conditions, highlighting the need for development of effective vaccines for these viruses, especially for parainfluenza and RSV. Expand
Association of invasive pneumococcal disease with season, atmospheric conditions, air pollution, and the isolation of respiratory viruses.
The finding, with regard to children, that correlations tended to be stronger for events that occurred 1 month previously than for those that occurred contemporaneously is consistent with the concept that viral or allergic events predispose to otitis media with effusion, which becomes suppurative and leads to pneumococcal bacteremia or meningitis. Expand
Respiratory viral infections in patients with chronic, obstructive pulmonary disease
Respiratory viral infections are commonly associated with acute respiratory illness in COPD patients, and the use of RT-PCR assays significantly increases the ability to diagnose these infections. Expand
Epidemiologic patterns of acute lower respiratory disease of children in a pediatric group practice.
Comprehensive surveillance of acute lower respiratory illnesses of children seen in apediatric group practice was maintained for 67 months in Chapel Hill, North Carolina, and consistent patterns have been observed in the clinical manifestations, seasonal occurrence, and age and sex distribution of infections. Expand
Dual Respiratory Virus Infections
Eight prospective epidemiological studies conducted between 1991 and 1995 for dual respiratory virus infection (DRVI) were reviewed to determine the frequency, associated comorbid conditions, clinical presentations, and morbidity related to DRVI among immunocompetent persons. Expand
Maternal immunization with Haemophilus influenzae type b polysaccharide-tetanus protein conjugate vaccine in The Gambia.
In areas where much invasive Hib disease occurs in infants younger than 6 months, maternal immunization may help to reduce the risk of Hib disease in infants too young for immunization. Expand