• Publications
  • Influence
Modification of the Clinical Global Impressions (CGI) scale for use in bipolar illness (BP): the CGI-BP
The modified CGI-BP is anticipated to be more useful than the original CGI in studies of bipolar disorder and interrater reliability of the scale was demonstrated in preliminary analyses. Expand
The Netherlands Study of Depression and Anxiety (NESDA): rationale, objectives and methods
The Netherlands Study of Depression and Anxiety (NESDA) is a multi‐site naturalistic cohort study to: (1) describe the long‐term course and consequences of depressive and anxiety disorders, and (2)Expand
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
Empirical evidence of shared genetic etiology for psychiatric disorders can inform nosology and encourages the investigation of common pathophysiologies for related disorders. Expand
Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder.
Comorbid lifetime and current axis I disorders in 288 patients with bipolar disorder and the relationships of these comorbid disorders to selected demographic and historical illness variables showed associations with earlier age at onset of affective symptoms and syndromal bipolar disorder. Expand
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar
The Canadian Network for Mood and Anxiety Treatments published guidelines for the management of bipolar disorder in 2005, with updates in 2007 and 2009. This third update, in conjunction with theExpand
Factors associated with suicide attempts in 648 patients with bipolar disorder in the Stanley Foundation Bipolar Network.
It is indicated that a history of suicide attempts is associated with a more difficult course of bipolar disorder and the occurrence of more psychosocial stressors at many different time domains. Expand
A mega-analysis of genome-wide association studies for major depressive disorder
Although this is the largest genome-wide analysis of MDD yet conducted, its high prevalence means that the sample is still underpowered to detect genetic effects typical for complex traits, and it was unable to identify robust and replicable findings. Expand
Duration of major depressive episodes in the general population: Results from the Netherlands Mental Health Survey and Incidence Study (NEMESIS)
Although half of those affected with MDE recovered rapidly, the risk of chronicity (duration 24months or more) was considerable and underlines the necessity of diagnosing and treating those at risk. Expand
The Stanley Foundation Bipolar Treatment Outcome Network. II. Demographics and illness characteristics of the first 261 patients.
The SFBN represents a sample of predominantly BP I patients largely recruited from the community who will be followed in detail longitudinally, participate in clinical trials, and thus help advance the understanding and treatment of this life-threatening medical disorder. Expand
Early physical and sexual abuse associated with an adverse course of bipolar illness
Greater appreciation of the association of early traumatic experiences and an adverse course of bipolar illness should lead to preventive and early intervention approaches that may lessen the associated risk of a poor outcome. Expand