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Effectiveness of antiretroviral therapy among HIV-infected children in sub-Saharan Africa.
- C. Sutcliffe, J. V. van Dijk, C. Bolton, D. Persaud, W. Moss
- The Lancet. Infectious diseases
- 1 August 2008
Assessment of antiretroviral treatment programmes for HIV-infected children in sub-Saharan Africa is important to enable the development of effective care and improve treatment outcomes. We review… Expand
Safety and efficacy of zinc supplementation for children with HIV-1 infection in South Africa: a randomised double-blind placebo-controlled trial
BACKGROUND Zinc deficiency is associated with impaired immune function and an increased risk of infection. Supplementation can decrease the incidence of diarrhoea and pneumonia in children in… Expand
Global measles elimination
Measles remains a leading vaccine-preventable cause of child mortality worldwide, particularly in sub-Saharan Africa where almost half of the estimated 454,000 measles deaths in 2004 occurred.… Expand
Haemophilus influenzae type b conjugate vaccine use and effectiveness.
Haemophilus influenzae type b (Hib) is an important cause of invasive bacterial disease in children, including meningitis and pneumonia. The introduction of Hib conjugate vaccines into routine… Expand
Differential regulation of interleukin (IL)-4, IL-5, and IL-10 during measles in Zambian children.
To determine the effect of measles virus infection on cytokine production in children from sub-Saharan Africa, temporal changes in cytokine production in vivo were analyzed and the T cell sources of… Expand
The association of Blastocystis hominis and Endolimax nana with diarrheal stools in Zambian school-age children
- T. Graczyk, C. Shiff, L. Tamang, Fair Munsaka, A. Beitin, W. Moss
- Biology, Medicine
- Parasitology Research
- 26 October 2005
To determine the prevalence of endoparasites and their association with diarrhea, a survey was conducted in the Southern Province of Zambia that used conventional and molecular techniques applied to… Expand
High burden of malaria following scale-up of control interventions in Nchelenge District, Luapula Province, Zambia
BackgroundMalaria control interventions have been scaled-up in Zambia in conjunction with a malaria surveillance system. Although substantial progress has been achieved in reducing morbidity and… Expand
Weight and height z-scores improve after initiating ART among HIV-infected children in rural Zambia: a cohort study
BackgroundDeficits in growth observed in HIV-infected children in resource-poor settings can be reversed with antiretroviral treatment (ART). However, many of the studies have been conducted in urban… Expand
Increased prevalence of the pfdhfr/phdhps quintuple mutant and rapid emergence of pfdhps resistance mutations at codons 581 and 613 in Kisumu, Kenya
- Maroya D. Spalding, Fredrick Eyase, +5 authors N. Waters
- Biology, Medicine
- Malaria Journal
- 24 November 2010
BackgroundAnti-malarial drug resistance in Kenya prompted two drug policy changes within a decade: sulphadoxine-pyrimethamine (SP) replaced chloroquine (CQ) as the first-line anti-malarial in 1998… Expand
Risk Factors for Pre-Treatment Mortality among HIV-Infected Children in Rural Zambia: A Cohort Study
Background Many HIV-infected children in sub-Saharan Africa enter care at a late stage of disease. As preparation of the child and family for antiretroviral therapy (ART) can take several clinic… Expand