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Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III.
From a total of 22 hypertriglyceridemic subjects tested, 14 subjects were selected on the basis of normal postheparin plasma lipoprotein lipase (LPL) levels and the presence of LPL inhibitoryExpand
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Evaluation of synthetic/reconstituted high-density lipoproteins as delivery vehicles for paclitaxel
Reconstituted (synthetic) high-density lipoprotein particles carrying paclitaxel (rHDL/PTX) were prepared with substantially higher PTX content than reported earlier. The rHDL/PTX complexes seemed toExpand
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Structure and functional properties of lipoprotein lipase.
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High density lipoprotein complexes as delivery vehicles for anticancer drugs.
MATERIALS AND METHODS Recombinant high density lipoprotein (rHDL) particles were prepared with defined composition (phosphatidylcholine, apolipoprotein A-1, cholesterol and cholesteryl esters) and aExpand
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Receptor mediated uptake of paclitaxel from a synthetic high density lipoprotein nanocarrier
The purpose of these studies was to determine the mechanism(s) whereby paclitaxel (PTX), is taken up by cancer cells, once encapsulated into synthetic/reconstituted high density lipoprotein (rHDL).Expand
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Intra-ocular pressure changes during maximal isometric contraction: does this reflect intra-cranial pressure or retinal venous pressure?
Recent publications have suggested that intra-ocular pressure (IOP) may be an indirect assessment of intra-cranial pressure (ICP). Both IOP and ICP have similar physiologic pressure ranges andExpand
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Sudden cardiac death in a 20-year-old bodybuilder using anabolic steroids.
Anabolic steroid use is widespread and has been associated with a variety of pathological conditions. The subject of this case is a 20-year-old amateur bodybuilder who died of sudden cardiopulmonaryExpand
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Anabolic steroid-induced hepatotoxicity: is it overstated?
OBJECTIVE There have been numerous reports of hepatic dysfunction secondary to anabolic steroid use based on elevated levels of serum aminotransferases. This study was conducted to distinguishExpand
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Evaluation of Serum-Lipid-Related Cardiovascular Risk Factors in Alzheimer’s Disease
There is now sufficient evidence to suggest that cardiovascular pathology and altered lipid metabolism contribute to the development of late-onset Alzheimer’s disease (AD). In the present study, 24Expand
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Studies on the composition and structure of plasma lipoproteins. Distribution of lipoprotein families in major density classes of normal human plasma lipoproteins.
Abstract To account for the protein heterogeneity of lipoprotein preparations isolated by ultracentrifugal or precipitation techniques, we have proposed a classification system [P. Alaupovic et al.,Expand
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