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Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis.
TLDR
There is now emerging and compelling evidence that many high grade serous carcinomas (by far the most common subtype of ovarian carcinoma) actually arise from the epithelium of the distal fallopian tube, and future studies regarding the initiating molecular events in the development of this aggressive neoplasm should concentrate on this site. Expand
A common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization (WHO) expert consensus proposal
TLDR
This work believes this conceptual approach can form the basis for the next generation of NEN classifications and will allow more consistent taxonomy to understand how neoplasms from different organ systems inter-relate clinically and genetically. Expand
p16 Expression in the Female Genital Tract and Its Value in Diagnosis
TLDR
In cervical squamous lesions, p16 is positive in most high-grade cervical intraepithelial neoplasia (CIN) and in some cases of low-grade CIN, usually those associated with high-risk HPV, whereas the more common non-HPV-associated neoplasms are largely negative or focally positive. Expand
Hormone receptor‐negative, thyroid transcription factor 1‐positive uterine and ovarian adenocarcinomas: report of a series of mesonephric‐like adenocarcinomas
TLDR
A series of uterine corpus and ovarian neoplasms are reported which are believed to represent mesonephric adenocarcinomas based on their characteristic morphology and immunophenotype. Expand
ESMO-ESGO consensus conference recommendations on ovarian cancer: pathology and molecular biology, early and advanced stages, borderline tumours and recurrent disease†.
TLDR
The recommendations presented here are based on the best available evidence and expert agreement and are presented with a summary of evidence supporting each recommendation. Expand
The European Society of Gynaecological Oncology/European Society for Radiotherapy and Oncology/European Society of Pathology Guidelines for the Management of Patients with Cervical Cancer
TLDR
The guidelines cover comprehensively staging, management, and follow-up for patients with cervical cancer and principles of radiotherapy and pathological evaluation are defined. Expand
Genomic Analysis Reveals the Molecular Heterogeneity of Ovarian Clear Cell Carcinomas
TLDR
OCCCs constitute a heterogeneous disease at the genomic level despite having similar histological features, and the pattern of genomic aberrations in subgroups of OCCCs is of clinical significance. Expand
Luteinized Thecomas (Thecomatosis) of the Type Typically Associated With Sclerosing Peritonitis: A Clinical, Histopathologic, and Immunohistochemical Analysis of 27 Cases
TLDR
It is documented for the first time that sclerosing peritonitis is not invariably associated with the distinctive ovarian pathology present in these cases, and it is reasonable to have the designation “thecomatosis” as a parenthetical alternative. Expand
An Immunohistochemical Study of Cervical Neuroendocrine Carcinomas: Neoplasms That are Commonly TTF1 Positive and Which May Express CK20 and P63
TLDR
It is illustrated that a proportion of cervical neuroendocrine carcinomas are negative with broad spectrum cytokeratins and some of the commonly used neuro endocrine markers, similar to that described in SCNECs in other organs. Expand
Chemotherapy or upfront surgery for newly diagnosed advanced ovarian cancer: Results from the MRC CHORUS trial.
TLDR
CHORUS was designed to demonstrate non-inferiority of NACT, excluding a 6% absolute detriment in 3yr survival from 50% expected with PS (1-sided alpha 10%). Expand
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