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Numerical Parametric Study of Paravalvular Leak Following a Transcatheter Aortic Valve Deployment Into a Patient-Specific Aortic Root.
Paravalvular leak (PVL) is a relatively frequent complication after transcatheter aortic valve replacement (TAVR) with increased mortality. Currently, there is no effective method to pre-operativelyExpand
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Development of an In Vitro Model to Characterize the Effects of Transcatheter Aortic Valve on Coronary Artery Flow.
Impairment of coronary artery flow, in either acute or chronic conditions, is a severe complication of transcatheter aortic valve (TAV) implantation, which can arise due to improper TAV positioning.Expand
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Eyelashes divert airflow to protect the eye
Eyelashes are ubiquitous, although their function has long remained a mystery. In this study, we elucidate the aerodynamic benefits of eyelashes. Through anatomical measurements, we find that 22Expand
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The Impact of Self-Expandable Transcatheter Aortic Valve Replacement on Concomitant Functional Mitral Regurgitation: A Comprehensive Engineering Analysis
ABSTRACT Background : Mitral regurgitation (MR) is present in a large proportion of patients who undergo transcatheter aortic valve replacement (TAVR). However, existing clinical data on the impactExpand
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Stiffness Dependent Separation of Cells in a Microfluidic Device
Abnormal cell mechanical stiffness can point to the development of various diseases including cancers and infections. We report a new microfluidic technique for continuous cell separation utilizingExpand
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Anisotropic micro- and nano-capsules.
In this work, we introduce anisotropically shaped, ultrathin micro- and nano-capsules fabricated by layer-by-layer approach. The original cubic and tetrahedral shapes of the template particles wereExpand
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Fluid–Structure Interaction Study of Transcatheter Aortic Valve Dynamics Using Smoothed Particle Hydrodynamics
  • W. Mao, K. Li, Wei Sun
  • Materials Science, Medicine
  • Cardiovascular engineering and technology
  • 14 November 2016
Computational modeling of heart valve dynamics incorporating both fluid dynamics and valve structural responses has been challenging. In this study, we developed a novel fully-coupled fluid–structureExpand
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Fully-coupled fluid-structure interaction simulation of the aortic and mitral valves in a realistic 3D left ventricle model
In this study, we present a fully-coupled fluid-structure interaction (FSI) framework that combines smoothed particle hydrodynamics (SPH) and nonlinear finite element (FE) method to investigate theExpand
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Mesoscale modeling: solving complex flows in biology and biotechnology.
Fluids are involved in practically all physiological activities of living organisms. However, biological and biorelated flows are hard to analyze due to the inherent combination of interdependentExpand
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Modeling Left Ventricular Blood Flow Using Smoothed Particle Hydrodynamics
This study aims to investigate the capability of smoothed particle hydrodynamics (SPH), a fully Lagrangian mesh-free method, to simulate the bulk blood flow dynamics in two realistic left ventricularExpand
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