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Targeted photodynamic therapy via receptor mediated delivery systems.
- W. M. Sharman, J. V. van Lier, C. Allen
- Chemistry, Medicine
- Advanced drug delivery reviews
- 13 January 2004
Targeted photodynamic therapy (PDT) offers the opportunity of enhancing photodynamic efficiency by directly targeting diseased cells and tissues. While antibody-conjugates have received the most… Expand
Current status of phthalocyanines in the photodynamic therapy of cancer
Photodynamic therapy is a binary treatment now accepted in clinic for various malignancies in several countries around the world. Phthalocyanine molecules are second-generation photosensitizers with… Expand
Photodynamic Properties of Amphiphilic Derivatives of Aluminum Tetrasulfophthalocyanine¶
- C. Allen, R. Langlois, W. M. Sharman, C. La Madeleine, J. V. van Lier
- Medicine, Chemistry
- Photochemistry and photobiology
- 1 August 2002
Abstract Photodynamic therapy (PDT) is a promising treatment modality that has recently been accepted in clinics as a curative or palliative therapy for cancer and other nonmalignant conditions.… Expand
Role of activated oxygen species in photodynamic therapy.
Publisher Summary Knowledge of photodynamic therapy has increased substantially. So much so that it is now an approved treatment for various cancers and subsequent uses for PDT are being determined… Expand
Use of palladium catalysis in the synthesis of novel porphyrins and phthalocyanines
Palladium catalysts offer a rich and highly versatile chemistry for the synthesis of novel porphyrins and phthalocyanines. These mild and flexible reactions have been used extensively in the… Expand
Attenuation of photodynamically induced apoptosis by an RGD containing peptide.
- C. Allen, W. M. Sharman, C. La Madeleine, J. V. van Lier, J. Weber
- Medicine, Chemistry
- Photochemical & photobiological sciences…
- 10 April 2002
Research efforts have focused on the improvement of already established photodynamic therapy (PDT) protocols. The use of adjunct therapies is one such route. The integrin class of receptors mediates… Expand
Novel water-soluble phthalocyanines substituted with phosphonate moieties on the benzo rings
Abstract The synthesis and characterization of a series of phthalocyanine derivatives bearing phosphonate substituents directly bound to the aromatic rings of the phthalocyanine is described. These… Expand
Photodynamic Therapy: Targeting Cancer Cells with Photosensitizer-Bioconjugates
A new procedure for the synthesis of water-soluble tri- cationic and -anionic phthalocyanines
A series of water-soluble tri-anionic and -cationic substituted phthalocyanines has been synthesized via iodinated boron subphthalocyanines. The latter were opened with differently substituted… Expand