• Publications
  • Influence
Histamine release in dogs by Cremophor El® and its derivatives: Oxethylated oleic acid is the most effective constituent
Several preparations of Cremophor El®, several of other non-ionic detergents and several components of Cremophor El were tested for their histamine-releasing capacity in dogs. Lutensol AP 10 and aExpand
  • 118
  • 3
Histamine release in man
  • W. Lorenz
  • Chemistry, Medicine
  • Agents and Actions
  • 1 December 1975
Conclusions(1)Histamine release in man could be demonstrated using the fluorometric histamine assay in plasma as a reliable test.(2)Histamine release in animals may be relevant in some cases forExpand
  • 34
  • 2
Human intestinal diamine oxidase: Substrate specificity and comparative inhibitor study
For an 80-fold purified preparation of human intestinal diamine oxidase the optimum conditions of incubation, the substrate and the inhibitor specificity were tested. Putrescine was the most favouredExpand
  • 16
  • 2
An improved method for the determination of histamine release in man: its application in studies with propanidid and thiopentone.
Abstract Histamine release by propanidid and thiopentone was demonstrated with the use of a highly sensitive and specific method for determining histamine in human plasma. 5 min after i.v.Expand
  • 36
  • 1
Human intestinal diamine oxidase (DAO) activity in Crohn's disease: A new marker for disease assessment?
AbstractThe key-enzyme for the metabolism of diamines in man is diamine oxidase (DAO). Its highest activities are in the intestinal mucosa, localized in the cytoplasm of the mature enterocytes of theExpand
  • 37
  • 1
H1+H2-receptor antagonists for premedication in anaesthesia and surgery: A critical view based on randomized clinical trials with haemaccel and various antiallergic drugs
AbstractHistamine release by drugs used in anaesthesia and surgery has been often demonstrated in human volunteers, but only occasionally in patients. Three questions arose from these studies. (1) IsExpand
  • 31
  • 1
Histamine and peptic ulcer: A prospective study of mucosal histamine concentration in duodenal ulcer patients and in control subjects suffering from various gastrointestinal diseases
ZusammenfassungIn einer prospektiven Studie wurde der Histamingehalt der Korpusschleimhaut bei 100 Patienten gemessen. Diese Patienten schließen Kontrollpersonen, Ulkus-duodeni-Träger und solche mitExpand
  • 17
  • 1
  • Open Access
Plasma histamine levels in patients in the course of several standard operations: Influence of anaesthesia, surgical trauma and blood transfusion
SummaryA prospective controlled clinical trial was conducted on changes in plasma histamine and catecholamine levels during 5 standard operations. This communication, as the first part of the trial,Expand
  • 14
  • 1
  • Open Access
Structural requirements of imidazole compounds to be inhibitors or activators of histamine methyltransferase: Investigation of histamine analogues and H2-receptor antagonists
The influence of imidazole compounds (histamine analogues and H2-receptor antagonists) and of the specific histamine H2-receptor agonist dimaprit on histamine methyltransferase (HMT) from pig gastricExpand
  • 10
  • 1