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Effect of conjugated linoleic acid on body composition in mice
The effects of conjugated linoleic acid (CLA) on body composition were investigated. ICR mice were fed a control diet containing 5.5% corn oil or a CLA-supplemented diet (5.0% corn oil plus 0.5%Expand
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Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions
GPCR Close-Up Structures of G protein–coupled receptors (GPCRs) determined in the past few years, have provided insight into the function of this important family of membrane proteins. Liu et al. (p.Expand
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Structure of the human smoothened receptor bound to an antitumour agent
The smoothened (SMO) receptor, a key signal transducer in the hedgehog signalling pathway, is responsible for the maintenance of normal embryonic development and is implicated in carcinogenesis. ItExpand
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Structure of the human histamine H1 receptor complex with doxepin
The biogenic amine histamine is an important pharmacological mediator involved in pathophysiological processes such as allergies and inflammations. Histamine H1 receptor (H1R) antagonists are veryExpand
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Structure of the human glucagon class B G-protein-coupled receptor
Binding of the glucagon peptide to the glucagon receptor (GCGR) triggers the release of glucose from the liver during fasting; thus GCGR plays an important role in glucose homeostasis. Here we reportExpand
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Evidence that the trans-10,cis-12 isomer of conjugated linoleic acid induces body composition changes in mice
We investigated the effects of conjugated linoleic acid (CLA) preparations, which were enriched for the cis-9,trans-11 CLA isomer or the trans-10,cis-12 CLA isomer, on body composition in mice. BodyExpand
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Structure of the human kappa opioid receptor in complex with JDTic
Opioid receptors mediate the actions of endogenous and exogenous opioids on many physiological processes, including the regulation of pain, respiratory drive, mood, and—in the case of κ-opioidExpand
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Structure of the Nociceptin/Orphanin FQ Receptor in Complex with a Peptide Mimetic
Members of the opioid receptor family of G-protein-coupled receptors (GPCRs) are found throughout the peripheral and central nervous system, where they have key roles in nociception and analgesia.Expand
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Changes in body composition in mice during feeding and withdrawal of conjugated linoleic acid
Two experiments were conducted. In Experiment 1, 8-wk-old mice were fed control diet or diet supplemented with 0.5% conjugated linoleic acid (CLA) to study the effect of CLA on body composition (CLA:Expand
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Development and evaluation of silk fibroin-based nerve grafts used for peripheral nerve regeneration.
Silk fibroin (SF), derived from natural silk long used as a textile material, has recently become an important biomaterial for tissue engineering applications. We have previously reported on good inExpand
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