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Interplay between the Westerlies and Asian monsoon recorded in Lake Qinghai sediments since 32 ka
Two atmospheric circulation systems, the mid-latitude Westerlies and the Asian summer monsoon (ASM), play key roles in northern-hemisphere climatic changes. However, the variability of the WesterliesExpand
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Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection.
PURPOSE To describe the pharmacokinetics occurring after the direct injection of triamcinolone acetonide into the vitreous humor of humans. DESIGN Interventional case series. PARTICIPANTS FiveExpand
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Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy.
The worldwide increase in the prevalence of multi-antibiotic-resistant bacteria has threatened the physician's ability to provide appropriate therapy for infections. The relationship betweenExpand
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Pharmacodynamics of Caspofungin in a Murine Model of Systemic Candidiasis: Importance of Persistence of Caspofungin in Tissues to Understanding Drug Activity
ABSTRACT Pharmacokinetic and pharmacodynamic studies were conducted in a murine model of systemic candidiasis to determine the pharmacodynamic parameter linked with caspofungin efficacy. AdditionalExpand
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Highly Efficient Doubled-Haploid Production in Wheat ( Triticum aestivum L.) via Induced Microspore Embryogenesis
An efficient doubled-haploid production technology that induces homozygosity can greatly reduce the time and cost of cultivar development. Low efficiency of doubled-haploid production previously hasExpand
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Concentration-Dependent Mycobacterium tuberculosis Killing and Prevention of Resistance by Rifampin
ABSTRACT Rifampin is a cornerstone of modern antituberculosis therapy. However, rifampin's half-life of 3 h is believed to limit its utility for intermittent therapy, so new congeners with longExpand
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CUDA-MEME: Accelerating motif discovery in biological sequences using CUDA-enabled graphics processing units
Motif discovery in biological sequences is of prime importance and a major challenge in computational biology. Consequently, numerous motif discovery tools have been developed to date. However, theExpand
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Streaming Algorithms for Biological Sequence Alignment on GPUs
Sequence alignment is a common and often repeated task in molecular biology. Typical alignment operations consist of finding similarities between a pair of sequences (pairwise sequence alignment) orExpand
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Most C6 cells are cancer stem cells: evidence from clonal and population analyses.
Cancer stem cells have been isolated from human gliomas and many other parenchymal tumors. It was previously assumed that many established malignant cell lines also contain a rare subpopulation ofExpand
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Effects of therapeutic mild hypothermia on patients with severe traumatic brain injury after craniotomy.
PURPOSE We investigated the effects of therapeutic mild hypothermia on patients with severe traumatic brain injury after craniotomy (TBI). METHODS Eighty patients with severe TBI after unilateralExpand
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