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Sodium Hydrosulfide Attenuates Beta-Amyloid-Induced Cognitive Deficits and Neuroinflammation via Modulation of MAPK/NF-κB Pathway in Rats.
Beta-amyloid (Aβ), a neurotoxic peptide, accumulates in the brain of Alzheimer's disease (AD) subjects to initiate neuroinflammation eventually leading to memory impairment. Here, we demonstrated… Expand
Propofol Affects Neurodegeneration and Neurogenesis by Regulation of Autophagy via Effects on Intracellular Calcium Homeostasis
Background: In human cortical neural progenitor cells, we investigated the effects of propofol on calcium homeostasis in both the ryanodine and inositol 1,4,5-trisphosphate calcium release channels.… Expand
VASP phosphorylation and genetic polymorphism for clopidogrel resistance in Chinese patients with non-cardioembolic ischemic stroke.
- S. Zhang, Xinqiang Lai, W. Li, Zhilin Xiong, A. Xu, L. Huang
- Thrombosis research
- 1 December 2014
BACKGROUND Clopidogrel resistance(CR)is found in non-cardioembolic ischemic stroke (NCIS) patients. However, it is still largely unknown how to identify CR in NCIS patients by laboratory and genetic… Expand
Molecular cloning of a thaumatin-like protein gene from Pyrus pyrifolia and overexpression of this gene in tobacco increased resistance to pathogenic fungi
Thaumatin-like proteins (TLPs) belong to the pathogenesis-related proteins 5 family, and members of TLP gene family accumulate in plants in response to pathogen infection or environmental stress. The… Expand
The miR-29b-Sirt1 axis regulates self-renewal of mouse embryonic stem cells in response to reactive oxygen species.
- Zengguang Xu, L. Zhang, X. Fei, Xiuwen Yi, W. Li, Q. Wang
- Biology, Medicine
- Cellular signalling
- 1 July 2014
Endogenous reactive oxygen species (ROS) control is important for the maintenance of self-renewal of embryonic stem (ES) cells. Although miRNAs have been found to be critically involved in the… Expand
Postoperative adverse respiratory events in preschool patients with inhaled foreign bodies: an analysis of 505 cases
Objectives: To identify the risk factors associated with postoperative adverse respiratory events in preschool‐aged children with inhaled foreign bodies (FBs) undergoing rigid bronchoscopy.
Tracheal extubation of deeply anesthetized pediatric patients: a comparison of sevoflurane and sevoflurane in combination with low‐dose remifentanil
Purpose: We aimed to observe the emergence characteristics of children tracheally extubated in deep anesthesia with sevoflurane or sevoflurane in combination with low‐dose remifentanil.
A β-1,3-glucanase gene expressed in fruit of Pyrus pyrifolia enhances resistance to several pathogenic fungi in transgenic tobacco
Abstractβ-1,3-glucanases, one of the well known families of pathogenesis-related (PR) proteins in responding to pathogen infection or some environmental stresses, are hydrolytic enzymes abundant in… Expand
Synthesis, cytotoxicity and DNA-binding levels of new type binuclear platinum(II) complexes.
- J. Zhang, Y. Li, +6 authors J. Wu
- Chemistry, Medicine
- European journal of medicinal chemistry
- 1 November 2009
Six new type binuclear platinum(II) complexes (a-f) have been synthesized and characterized by elemental analysis, conductivity, thermal analysis, IR, UV, (1)H NMR and mass spectra techniques. The… Expand
Prognostic study of sevoflurane-based general anesthesia on cognitive function in children
PurposeIt is unclear whether volatile general anesthetics have sustained adverse effects on the immature brains of children. We performed a self-controlled study to evaluate the effects of strabismus… Expand