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Chiral gravity in three dimensions
Three dimensional Einstein gravity with negative cosmological constant ?1/?2 deformed by a gravitational Chern-Simons action with coefficient 1/? is studied in an asymptotically AdS3 spacetime. It isExpand
IsoLasso: A LASSO Regression Approach to RNA-Seq Based Transcriptome Assembly
The new second generation sequencing technology revolutionizes many biology-related research fields and poses various computational biology challenges. Expand
The Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Inhibits Type I Interferon Production by Interfering with TRIM25-Mediated RIG-I Ubiquitination
  • Y. Hu, W. Li, +6 authors C. Cao
  • Medicine, Biology
  • Journal of Virology
  • 1 February 2017
ABSTRACT Severe acute respiratory syndrome (SARS) is a respiratory disease, caused by a coronavirus (SARS-CoV), that is characterized by atypical pneumonia. The nucleocapsid protein (N protein) ofExpand
Yeast Model Uncovers Dual Roles of Mitochondria in the Action of Artemisinin
Artemisinins, derived from the wormwood herb Artemisia annua, are the most potent antimalarial drugs currently available. Despite extensive research, the exact mode of action of artemisinins has notExpand
Yeast AMID homologue Ndi1p displays respiration-restricted apoptotic activity and is involved in chronological aging.
Apoptosis-inducing factor (AIF) and AIF-homologous mitochondrion-associated inducer of death (AMID) are both mitochondrial flavoproteins that trigger caspase-independent apoptosis. PhylogeneticExpand
A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students
ABSTRACT Engaging large numbers of undergraduates in authentic scientific discovery is desirable but difficult to achieve. We have developed a general model in which faculty and teaching assistantsExpand
Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody
The MERS-CoV is an emerging virus, which already infected more than 1,300 humans with high (∼36%) mortality. Here, we show that m336, an exceptionally potent human anti-MERS-CoV antibody, is almostExpand
Inference of Isoforms from Short Sequence Reads
We propose a method to calculate the expression levels of isoforms and infer isoforms from short RNA-Seq reads using exon-intron boundary, transcription start site (TSS) and poly-A site (PAS) information. Expand
Spectral Signatures of Coral Reefs: Features from Space
The spectral signatures of coral reefs and related scenes, as they would be measured above the Earth's atmosphere, are calculated using a coupled atmosphere-ocean discrete ordinates radiativeExpand
DP-GAN: Diversity-Promoting Generative Adversarial Network for Generating Informative and Diversified Text
We propose a novel language-model based discriminator, which can better distinguish novel text from repeated text without the saturation problem compared with existing classifier-based discriminators. Expand