• Publications
  • Influence
BMP10 is essential for maintaining cardiac growth during murine cardiogenesis
During cardiogenesis, perturbation of a key transition at mid-gestation from cardiac patterning to cardiac growth and chamber maturation often leads to diverse types of congenital heart disease, suchExpand
  • 387
  • 27
  • PDF
Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution
Lampreys are representatives of an ancient vertebrate lineage that diverged from our own ∼500 million years ago. By virtue of this deeply shared ancestry, the sea lamprey (P. marinus) genome isExpand
  • 505
  • 26
  • PDF
CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo
The platelet glycoprotein IIb (αIIb; CD41) constitutes the alpha subunit of a highly expressed platelet surface integrin protein. We demonstrate that CD41 serves as the earliest marker of primitiveExpand
  • 322
  • 26
  • PDF
Bile Acid Secreted by Male Sea Lamprey That Acts as a Sex Pheromone
We show that reproductively mature male sea lampreys release a bile acid that acts as a potent sex pheromone, inducing preference and searching behavior in ovulated female lampreys. The secreted bileExpand
  • 335
  • 15
11-Deoxycortisol is a corticosteroid hormone in the lamprey
Corticosteroid hormones are critical for controlling metabolism, hydromineral balance, and the stress response in vertebrates. Although corticosteroid hormones have been well characterized in mostExpand
  • 81
  • 10
  • PDF
Direct behavioral evidence that unique bile acids released by larval sea lamprey (Petromyzon marinus) function as a migratory pheromone
Four behavioral experiments conducted in both the laboratory and the field provide evidence that adult sea lamprey (Petromyzon marinus) select spawning rivers based on the odor of larvae that theyExpand
  • 167
  • 10
High doses of bone morphogenetic protein 2 induce structurally abnormal bone and inflammation in vivo.
The major Food and Drug Association-approved osteoinductive factors in wide clinical use are bone morphogenetic proteins (BMPs). Although BMPs can promote robust bone formation, they also induceExpand
  • 381
  • 9
Extensive sequence divergence between the reference genomes of two elite indica rice varieties Zhenshan 97 and Minghui 63
  • J. Zhang, L. Chen, +34 authors Q. Zhang
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 17 August 2016
Significance Indica rice accounts for >70% of total rice production worldwide, is genetically highly diverse, and can be divided into two major varietal groups independently bred and widelyExpand
  • 110
  • 9
A synthesized pheromone induces upstream movement in female sea lamprey and summons them into traps
Female insect pheromone blends induce robust tracking responses in males and direct them into traps. In vertebrates, pheromones that induce strong and precise tracking responses in natural habitatsExpand
  • 156
  • 8
  • PDF
The sea lamprey Petromyzon marinus genome reveals the early origin of several chemosensory receptor families in the vertebrate lineage
BackgroundIn gnathostomes, chemosensory receptors (CR) expressed in olfactory epithelia are encoded by evolutionarily dynamic gene families encoding odorant receptors (OR), trace amine-associatedExpand
  • 50
  • 7
  • PDF