• Publications
  • Influence
Curcumin-mediated lifespan extension in Caenorhabditis elegans
Curcumin is the active ingredient in the herbal medicine and dietary spice, turmeric (Curcuma longa). It has a wide range of biological activities, including anti-inflammatory, antioxidant,Expand
  • 142
  • 9
Phthalates Induce Neurotoxicity Affecting Locomotor and Thermotactic Behaviors and AFD Neurons through Oxidative Stress in Caenorhabditis elegans
Background Phthalate esters are ubiquitous environmental contaminants and numerous organisms are thus exposed to various levels of phthalates in their natural habitat. Considering the critical, butExpand
  • 41
  • 2
  • PDF
Lung cancer risk in relation to traffic-related nano/ultrafine particle-bound PAHs exposure: a preliminary probabilistic assessment.
Exposures to carcinogenic polycyclic aromatic hydrocarbons (PAHs) have been linked to human lung cancer. The purpose of this study was to assess lung cancer risk caused by inhalation exposure toExpand
  • 64
  • 2
  • PDF
Protective Efficacy of Selenite against Lead-Induced Neurotoxicity in Caenorhabditis elegans
Background Selenium is an essential micronutrient that has a narrow exposure window between its beneficial and toxic effects. This study investigated the protective potential of selenite (IV) againstExpand
  • 33
  • 2
  • PDF
Caenorhabditis elegans bicarbonate transporter ABTS-1 is involved in arsenite toxicity and cholinergic signaling.
Arsenic poisoning affects millions of people worldwide. Although there is accumulating evidence to suggest that the nervous system is a target of arsenic, relatively little information is knownExpand
  • 9
  • 2
Selenite protects Caenorhabditis elegans from oxidative stress via DAF-16 and TRXR-1.
SCOPE Selenium is an essential micronutrient. In the present study, trace amount of selenite (0.01 μM) was evaluated for oxidative stress resistance and potential associated factors in CaenorhabditisExpand
  • 19
A low-complexity direction-of-arrival estimation algorithm for full-dimension massive MIMO systems
This paper proposes a two-stage low-complexity DoA estimation scheme, in which two MUSIC algorithms are performed for estimating, respectively, the elevation and azimuth angles of the impinging sources. Expand
  • 15
In vivo antioxidant activities of essential oils and their constituents from leaves of the Taiwanese Cinnamomum osmophloeum.
Cinnamomum osmophloeum Kaneh is an indigenous tree species in Taiwan. In this study, phytochemical characteristics and antioxidant activities of the essential oils and key constituents from theExpand
  • 32
Protein engineering of oxidosqualene-lanosterol cyclase into triterpene monocyclase.
A computational modeling/protein engineering approach was applied to probe H234, C457, T509, Y510, and W587 within Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase (ERG7), which spatiallyExpand
  • 17
  • PDF
Differential Stereocontrolled Formation of Tricyclic Triterpenes by Mutation of Tyrosine 99 of the Oxidosqualene-Lanosterol Cyclase from Saccharomyces cerevisiae
The function of the Tyr99 residue from Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase (ERG7) was analyzed by constructing deletion and site-saturated mutants. Two truncated intermediates,Expand
  • 11
  • PDF