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Long-term treatment of transfusional iron overload with the oral iron chelator deferiprone (L1): a Dutch multicenter trial
Abstract We performed an open, nonrandomized, multicenter phase-II trial to evaluate the efficacy and toxicity of 1 year of treatment with the oral iron chelator deferiprone in 38 mainlyExpand
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Methodology for the development of a drug library based upon collision-induced fragmentation for the identification of toxicologically relevant drugs in plasma samples.
The possibility of creating a robust mass spectral library with use of high-performance liquid chromatography-atmospheric pressure-electrospray ionization (HPLC-AP-ESI) for the identification ofExpand
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Citalopram serum and milk levels in mother and infant during lactation.
We present a case of intensified therapeutic drug monitoring (TDM) of citalopram in mother and newborn infant after clinically observed selective serotonin reuptake inhibitor (SSRI)-associatedExpand
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Accelerated elimination of thallium in the rat due to subchronic treatment with furosemide
In connection with a programme of investigations concerning the disposition of thallium in the rat and the influence of diuretic agents on the rate of elimination of thallium from the body, Tl2SO4Expand
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Use of Clonidine for Chemical Submission
Case Report: An East-European prostitute in Amsterdam robbed several victims, after having sedated them with clonidine solution (available as plastic ampoules of eyedrops) added to her victims'Expand
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Kinetic behaviour of thallium in the rat
Abstract1.In acute experiments anaesthetized rats were treated with a subthreshold dose of 204Tl+, given intravenously in order to study the elimination kinetics of Tl+. Thallium disappeared fromExpand
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Abstracts of papers
s of papers THE DETERMINATION OF ATRACURIUM AND ITS ~ METABOLITE LAUDANOSINE IN SERUM BY HPLC. D.R.A. Ugesl f H. Bloe~hof I and S. Aqoston 2. Atracurium is a novel his-quaternary (x~mpetitiveExpand
Pharmaceutical analysis of the oral iron chelator deferiprone (DMHP, L1)
The oral iron chelator deferiprone (1,2-dimethyl-3-hydroxypyrid-4-one, DMHP, L1 or CP20) can be a useful drug in patients with transfusional hemosiderosis. From 1987 about 1000 patients in 16Expand
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[Teaching to inhale: better utilization of powder inhalators after counseling and instruction].
OBJECTIVE To study the effect of instruction of patients who used an dry powder device on the correct performance of the inhalation technique and whether the effect lasts. DESIGN Prospective. Expand