• Publications
  • Influence
Analysis of ELP4, SRPX2, and interacting genes in typical and atypical rolandic epilepsy
Rolandic epilepsy (RE) and its atypical variants (atypical rolandic epilepsy, ARE) along the spectrum of epilepsy–aphasia disorders are characterized by a strong but largely unknown genetic basis.Expand
  • 42
  • 2
  • PDF
Ligand binding properties of human galanin receptors
Abstract The galanin receptor family comprises of three members, GalR1, GalR2 and GalR3, all belonging to the G-protein-couple receptor superfamily. All three receptors bind the peptide hormoneExpand
  • 10
  • 2
Determining receptor–ligand interaction of human galanin receptor type 3
Galanin is a neuropeptide found throughout the central and peripheral nervous systems of a wide range of species, ranging from human and mouse to frog and tuna. Galanin mediates its physiologicalExpand
  • 11
  • PDF
Identification of Selective Inhibitors of the Potassium Channel Kv1.1–1.2(3) by High-Throughput Virtual Screening and Automated Patch Clamp
Two voltage‐dependent potassium channels, Kv1.1 (KCNA1) and Kv1.2 (KCNA2), are found to co‐localize at the juxtaparanodal region of axons throughout the nervous system and are known to co‐assemble inExpand
  • 18
  • PDF
The early-stage intermediate
Abstract: The multistep polypeptide chain folding model presented in this chapter involves several intermediates, the first of which is called the early-stage (ES) intermediate. This intermediate isExpand
  • 9
The C-terminal cavity of the Na,K-ATPase analyzed by docking and electrophysiology
Abstract The Na,K-ATPase is essential to all animals, since it maintains the electrochemical gradients that energize the plasma membrane. Naturally occurring inhibitors of the pump from plants haveExpand
  • 5
  • PDF
Structural information involved in the interpretation of the stepwise protein folding process
Abstract: Calculating the quantity of information present in each step of the protein folding process suggests that the multistep approach requires less information than the one-step model.Expand
  • 6