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Naturally occurring cassane diterpenoids (CAs) of Caesalpinia: A systematic review of its biosynthesis, chemistry and pharmacology.
Natural products, especially diterpenoids, are enriched with numerous compounds with a broad spectrum of therapeutic indications, suggesting that functional moieties serve as a core pharmacophore.… Expand
In Silico Exploration of the Molecular Mechanism of Cassane Diterpenoids on Anti-inflammatory and Immunomodulatory Activity
- Y. Wang, Baichun Hu, +4 authors Huiyuan Gao
- Computer Science, Chemistry
- J. Chem. Inf. Model.
- 25 February 2019
In this study, 102 CA compounds were selected to explore the possible molecular mechanism of this class of natural products on anti-inflammatory and immunomodulatory activity using RA as a disease model through a series of in silico methods: chemical-similarity-based target prediction, molecular docking, and molecular dynamics simulation. Expand
Synthesis of Polystyrene Particles with Precisely Controlled Degree of Concaveness
Shape is an essential property of polymeric particles. Herein, we propose a simple method to synthesize polymeric particles with a well-controlled concave shape. Our method takes advantage of the… Expand
New cassane-type diterpenoids from kernels of Caesalpinia bonduc (Linn.) Roxb. and their inhibitory activities on phosphodiesterase (PDE) and nuclear factor-kappa B (NF-κB) expression.
In this paper, chemical investigation on the chloroform soluble fraction of seed kernels of Caesalpinia bonduc resulted in the isolation of five new cassane diterpenoids: norcaesalpinin O (1),… Expand
Research on the retention time of retention enema of Chinese Traditional Herbs at chen shi in patients with pelvic inflammatory disease
- W. Jing
- 6 March 2012
Objective To investigate the impact on the retention time of retention enema at chen shi in patients with sequelae of pelvic inflammatory disease.Methods 60 residential patients (from May 2009 to… Expand
Assessment of left atrial function and dyssynchrony by real time three-dimensional echocardiography predicts recurrence of paroxysmal atrial fibrillation after radiofrequency ablation.
- Y. Hong-ning, X. Ruiqin, +8 authors C. Wei
- European review for medical and pharmacological…
- 1 May 2018
OBJECTIVE Left atrial volume and function are associated with recurrence of paroxysmal atrial fibrillation (AF) after radiofrequency ablation. A relationship between left atrial mechanical… Expand
New phenylpropanoid-conjugated pentacyclic triterpenoids from the whole plants of Leptopus lolonum with their antiproliferative activities on cancer cells.
Most of Euphorbiaceae plants are considered as folk medicinal plants because of their various pharmacological effects. However, there are eight Leptopus genus plants which belong to Euphorbiaceae… Expand
Investigation on the " Four High" injury of acute instrument in clinical nurses and protective measures
Objective To understand the high risk types, high risk links and high risk factors(Four High)of acute instrument injury in clinical nurses, so as to provide basis for the establishment of scientific… Expand