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- Publications
- Influence
Electron cryo-microscopy shows how strong binding of myosin to actin releases nucleotide
- K. Holmes, I. Angert, F. J. Kull, W. Jahn, R. Schröder
- Chemistry, Medicine
- Nature
- 25 September 2003
Muscle contraction involves the cyclic interaction of the myosin cross-bridges with the actin filament, which is coupled to steps in the hydrolysis of ATP. While bound to actin each cross-bridge… Expand
Three-dimensional atomic model of F-actin decorated with Dictyostelium myosin S1
- R. Schröder, Dietmar J. Manstein, +4 authors James A. Spudich
- Chemistry, Medicine
- Nature
- 8 July 1993
ELUCIDATION of the molecular contacts between actin and myosin is central to understanding the force-generating process in muscle and other cells. Actin, a highly conserved globular protein found in… Expand
Forecasting fire growth using an inverse zone modelling approach
A new methodology to effectively forecast fire dynamics based on assimilation of sensor observations is presented and demonstrated. An inverse modelling approach with a two-zone model is used to… Expand
Argiotoxin636 inhibits NMDA-activated ion channels expressed in Xenopus oocytes
- A. Draguhn, W. Jahn, V. Witzemann
- Biology, Medicine
- Neuroscience Letters
- 11 November 1991
Argiotoxin636, a component of the spider venom of argiope species, was chemically synthesized together with a number of derivatives in order to analyse their blocking activity on mammalian glutamate… Expand
Synthesis, characterization and application of two nucleoside triphosphate analogues, GTPgammaNH(2) and GTPgammaF.
- M. Stumber, C. Herrmann, S. Wohlgemuth, H. R. Kalbitzer, W. Jahn, M. Geyer
- Medicine
- European journal of biochemistry
- 2002
Guanosine triphosphate nucleotide analogues such as GppNHp (also named GMPPNP) or GTPgammaS are widely used to stabilize rapidly hydrolyzing protein-nucleotide complexes and to investigate… Expand
Über Antamanid, XIV. Zur Wirkungsweise des Antamanids
- Theodor Wieland, H. Faulstich, +5 authors Alwine Schmitz
- Chemistry
- 1972
Synthese 5′-substituierter Adenosinderivate
- W. Jahn
- Chemistry
- 1 June 1965
Die bei nucleophilen Substitutionen storende Umlagerung des 5′-O-Tosyl-2′.3′-O-isopropyliden-adenosins zu einem „Cyclo-nucleosid-Salz” last sich durch N-Acylierung vermeiden. Damit werden… Expand
Vom Adenosin abgeleitete Thioäther und S‐Oxide
Aus Methyl-[adenosyl-(5′)]-sulfid wurden mit H2O2 oder mit Br2 zwei diastereomere S-Oxide erhalten, ein rechts- und ein linksdrehendes. Die linksdrehende Form zeigt an der Ratte blutdrucksenkende… Expand
Derivatization of ribosomes and of tRNA with an undecagold cluster : crystallographic and functional studies
- S. Weinstein, S. Weinstein, +9 authors A. Yonath
- Chemistry
- 1 August 1992
An undecagold cluster was covalently attached to whole ribosomes and to their small and large subunits prior to their crystallization. X-ray crystallographic data were collected from crystals of the… Expand
The association of actin and myosin in the presence of gamma-amido-ATP proceeds mainly via a complex with myosin in the closed conformation.
- W. Jahn
- Chemistry, Medicine
- Biochemistry
- 21 August 2007
The interaction of gamma-amido-ATP (ATPN) and its 2'(3')-O-methylanthraniloyl derivative (mantATPN) with skeletal myosin subfragment 1 (S1) and actomyosin (actoS1) was studied in stopped-flow… Expand