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Stability of pyridoxal-5-phosphate semicarbazone: applications in plasma vitamin B6 analysis and population surveys of vitamin B6 nutritional status.
The determination of pyridoxal-5-phosphate (PLP) and pyridoxal (PL) in plasma requires the availability of dark room facilities, due to the photosensitivity of these vitamin B6 vitamers. The factExpand
Vitamin B6 revisited. Evidence of subclinical deficiencies in various segments of the population and possible consequences thereof.
The importance of vitamin B6 in human nutrition is discussed with special reference to the possibility of undetected long-term subclinical deficiencies in the population at large. It is well knownExpand
A Method for identifying Small Amounts of Nitrosamines in Biological Material
SINCE the discovery by Magee and Barnes1 of the carcinogenic properties of dimethyl nitrosamine, numerous reports have appeared on various aspects of the chemistry and biological action ofExpand
A rapid g.l.c. procedure for the determination of codeine and norcodeine in biological fluids based on micro‐phase extraction techniques
Therapeutic serum concentrations of codeine can be virtually completely extracted and obtained sufficiently concentrated for g.c. measurement without distillation, by acid extraction of the drug fromExpand
Evidence for the Occurrence of N-Nitrosamines in Tobacco
THE possible significance of N-nitrosamines as aetiological factors in human carcinogenesis is based on the widespread occurrence of nitrosamine precursors (S-amines and nitrites) in biologicalExpand
Nitrosamines as environmental carcinogens. II. Evidence for the presence of nitrosamines in tobacco smoke condensate.
Summary Trace amounts of N -nitrosamines in biologic material were determined qualitatively and semiquantitatively by conversion of the nitrosamines into the corresponding asymmetrical hydrazines.Expand
The efficacy of a bismuth-protein-complex compound in the treatment of gastric and duodenal ulcers.
Plasma pyridoxal-5-phosphate level as risk index for coronary artery disease.
Preliminary evidence is presented that plasma pyridoxal-5-phosphate levels are considerably and significantly reduced (P less than 0.0001) in patients suffering from myocardial infarction whenExpand
A new g.c. procedure, based on nitrosation, for the simultaneous determination of propoxyphene and norpropoxyphene in biological material
BUCZKO, W., DE GAETANO, G. & GARATTINI, S. (1974). J. Pharm. Pharmac., 26, 814-815. BUCZKO, W., DE GAETANO, G. & GARATTINI, S. (1975). Zbid., 27,366-368. FUKS, p., LANMAN, R. C. & SCHANKER, L. S.Expand