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Na+/Ca2+ exchanger in Drosophila: cloning, expression, and transport differences.
cDNAs for the Na+/Ca2+ exchanger from Drosophila melanogaster (Dmel/Nck) have been cloned by homology screening using the human heart Na+/Ca2+ exchanger cDNA. The overall deduced protein structureExpand
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Phosphorylation and Other Conundrums of Na/Ca Exchanger, NCX1
Abstract:  The Na+/Ca2+ exchanger (NCX) is an important Ca2+ transport mechanism in virtually all cells in the body. There are three genes that control the expression of NCX in mammals. There are atExpand
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Distribution of ryanodine receptors in rat ventricular myocytes
Ryanodine receptors (RyRs) are the major ion channels in the sarcoplasmic reticulum responsible for Ca2+ release in muscle cells. Localization of RyRs is therefore critical to our understanding ofExpand
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Fluorescence lifetime imaging of intracellular calcium
Fluorescence lifetime imaging microscopy (FLIM) is a new methodology for studying the spatial and temporal dynamics of macromolecule, molecules, and ions in living cells. In FLIM image contrast isExpand
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Principles of Network Organization of T-Tubule Membranes in Health and Disease
Mechanical and functional behaviors of cardiac myocytes are largely determined by architectural arrangements of protein assemblies, membrane networks and organelles. Myofilaments and mitochondriaExpand