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Can WR-2721 be improved upon?
Carbon Storage and Sequestration as Mineral Carbonates
The U.S. Department of Energy has identified mineral sequestration as a promising CO2 sequestration technology option, converting anthropogenic CO2 and magnesium silicates into permanent carbonateExpand
Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System*
Background: Biochemical analysis of S. cerevisiae MMR mutants has been limited by a lack of reconstituted MMR reactions. Results: 3′ nick-directed Mlh1-Pms1-dependent endonuclease and reconstitutedExpand
An archaeal RadA paralog influences presynaptic filament formation.
Recombinases of the RecA family play vital roles in homologous recombination, a high-fidelity mechanism to repair DNA double-stranded breaks. These proteins catalyze strand invasion and exchangeExpand
Differential radioprotection of normal tissues by hydrophilic chemical protectors.
Analogous to certain radiosensitizers which are too hydrophilic to enter tumor cells, certain radioprotectors, because of their hydrophilicity, may also be hindered from entering tumor cells and thusExpand
Studies on the evolution of plasma kinins: Reptilian and avian blood
Abstract Contact with a foreign surface triggers the release of a plasma kinin in turtle or alligator plasma. The peptide cannot be distinguished from mammalian plasma kinins. The equivalent of 1.4Expand
A recombinase paralog from the hyperthermophilic crenarchaeon Sulfolobus solfataricus enhances SsoRadA ssDNA binding and strand displacement.
Homologous recombination (HR) is a major pathway for the repair of double-strand DNA breaks, a highly deleterious form of DNA damage. The main catalytic protein in HR is the essential RecA-familyExpand
Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners
Eukaryotic DNA mismatch repair (MMR) involves both exonuclease 1 (Exo1)-dependent and Exo1-independent pathways. We found that the unstructured C-terminal domain of Saccharomyces cerevisiae Exo1Expand
The properties of Msh2–Msh6 ATP binding mutants suggest a signal amplification mechanism in DNA mismatch repair
DNA mismatch repair (MMR) corrects mispaired DNA bases and small insertion/deletion loops generated by DNA replication errors. After binding a mispair, the eukaryotic mispair recognition complexExpand