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Y-Chromosome evidence for a northward migration of modern humans into Eastern Asia during the last Ice Age.
  • B. Su, J. Xiao, +18 authors L. Jin
  • Geography, Medicine
  • American journal of human genetics
  • 1 December 1999
The timing and nature of the arrival and the subsequent expansion of modern humans into eastern Asia remains controversial. Using Y-chromosome biallelic markers, we investigated the ancientExpand
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Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa.
Protease-activated receptor 2 (PAR2) is expressed by vascular endothelial cells and other cells in which its function and physiological activator(s) are unknown. Unlike PAR1, PAR3, and PAR4, PAR2 isExpand
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Genetic relationship of populations in China.
  • J. Chu, W. Huang, +11 authors L. Jin
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 29 September 1998
Despite the fact that the continuity of morphology of fossil specimens of modern humans found in China has repeatedly challenged the Out-of-Africa hypothesis, Chinese populations are underrepresentedExpand
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Adaptive genic evolution in the Drosophila genomes
Determining the extent of adaptive evolution at the genomic level is central to our understanding of molecular evolution. A suitable observation for this purpose would consist of polymorphic data onExpand
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Gene expression analysis using oligonucleotide arrays produced by maskless photolithography.
Microarrays containing 195,000 in situ synthesized oligonucleotide features have been created using a benchtop, maskless photolithographic instrument. This instrument, the Maskless Array SynthesizerExpand
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KCNQ1 gain-of-function mutation in familial atrial fibrillation.
Atrial fibrillation (AF) is a common cardiac arrhythmia whose molecular etiology is poorly understood. We studied a family with hereditary persistent AF and identified the causative mutation (S140G)Expand
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Expansion of CREB's DNA recognition specificity by Tax results from interaction with Ala-Ala-Arg at positions 282-284 near the conserved DNA-binding domain of CREB.
The transactivator protein of human T-lymphotropic virus type I (HTLV-I), Tax, forms multiprotein complexes with the ubiquitous transcription factor CREB and the CREB/ATF-1 heterodimer. TheExpand
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A comprehensive draft genome sequence for lupin (Lupinus angustifolius), an emerging health food: insights into plant–microbe interactions and legume evolution
Summary Lupins are important grain legume crops that form a critical part of sustainable farming systems, reducing fertilizer use and providing disease breaks. It has a basal phylogenetic positionExpand
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Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship
Using a multidimensional genomic data set on glioblastoma from The Cancer Genome Atlas, we identified hsa-miR-26a as a cooperating component of a frequently occurring amplicon that also contains CDK4Expand
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Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models.
Although immunosuppressant immunophilin ligands promote neurite outgrowth in vitro, their neurotrophic activities are clearly independent of their immunosuppressive activity. In the present report, aExpand
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