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Morphogenic Regulators Baby boom and Wuschel Improve Monocot Transformation[OPEN]
TLDR
A transformation approach involving overexpression of the maize (Zea mays) Baby boom (Bbm) and maize Wuschel2 (Wus2) genes, which produced high transformation frequencies in numerous previously nontransformable maize inbred lines is reported.
Hepatoprotective evaluation of the total flavonoids extracted from flowers of Abelmoschus manihot (L.) Medic: In vitro and in vivo studies.
TLDR
The results suggested that TFA protected mice against CCl4-induced liver injury through antioxidant stress and antiinflammatory effects, which justified the use of this plant in traditional medicine for the treatment of liver disease.
Activation of the Dormant Secondary Metabolite Production by Introducing Gentamicin-Resistance in a Marine-Derived Penicillium purpurogenum G59
TLDR
The present study demonstrated the effectiveness of a simple, yet practical approach to activate the production of dormant fungal secondary metabolites by introducing acquired resistance to aminoglycoside antibiotics, which could be applied to the studies for eliciting dormant metabolic potential of fungi to obtain cryptic secondary metabolites.
Nine New and Five Known Polyketides Derived from a Deep Sea-Sourced Aspergillus sp. 16-02-1
TLDR
Nine new C9 polyketides, named aspiketolactonol (1), aspilactonols A–F (2–7), aspyronol (9) and epiaspinonediol (11), were isolated together with five known polyketones from the secondary metabolites of an Aspergillus sp.
Activation of Dormant Secondary Metabolite Production by Introducing Neomycin Resistance into the Deep-Sea Fungus, Aspergillus versicolor ZBY-3
TLDR
The present study demonstrated the effectiveness of the ultrasound-mediated approach to activate silent metabolite production in fungi by introducing acquired resistance to aminoglycosides and its potential for discovering new compounds from silent fungal metabolic pathways.
Four new koumine metabolites in rat liver microsomes
TLDR
The metabolic pathway of koumine was proposed and the cytotoxic activities between kOUmine and its metabolites were also compared in the A549 cell line.
Two new benzofuran lignan glycosides from Gelsemium elegans
Abstract Two new benzofuran lignan glycosides, gelsemiunoside A and B, were isolated from the whole plant of Gelsemium elegans Benth. Their structures were elucidated on the basis of spectroscopic
Bactericidal effects of copper-bearing nano-montmorillonite on three aquatic pathogenic bacteria and two intestinal available bacteria in vitro
TLDR
The results showed that the germicidal effects on Aeromonas hudrophila,Vibrio parahaemolyticus and Pseudomonas fluorescens increased with the concentration, and the effects on Lactobacillus acidophilus and Bacillus subtilis also somewhat increased, but to lower extent.
Antitumor activity of two gelsemine metabolites in rat liver microsomes
Gelsemine is one of the major alkaloids from Gelsemium elegans Benth., which has been used as an antitumor remedy in clinic. In this paper, metabolism of gelsemine has been investigated in vitro in
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