• Publications
  • Influence
Glomerular number and size in autopsy kidneys: the relationship to birth weight.
BACKGROUND In the Southeast United States, African Americans have an estimated incidence of hypertension and end-stage renal disease (ESRD) that is five times greater than Caucasians. Higher rates ofExpand
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Reduced nephron number and glomerulomegaly in Australian Aborigines: a group at high risk for renal disease and hypertension.
Aborigines in remote areas of Australia have much higher rates of renal disease, as well as hypertension and cardiovascular disease, than non-Aboriginal Australians. We compared kidney findings inExpand
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Biomarkers in chronic kidney disease: a review.
Chronic kidney disease (CKD) is a major public health problem. The classification of CKD by KDOQI and KDIGO and the routine eGFR reporting have resulted in increased identification of CKD. It isExpand
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Human nephron number: implications for health and disease
Several studies have shown that total nephron (glomerular) number varies widely in normal human kidneys. Whereas the studies agree that average nephron number is approximately 900,000 to 1 millionExpand
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Renal function and cardiovascular risk markers in a remote Australian Aboriginal community.
BACKGROUND Australian Aborigines living in remote areas have exceedingly high rates of renal failure together with increased cardiovascular morbidity and mortality. To examine the basis of thisExpand
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A new dimension to the Barker hypothesis: low birthweight and susceptibility to renal disease.
BACKGROUND There is an epidemic of renal failure among Aborigines in the Australia's Northern Territory. The incidence is more than 1000 per million, and is doubling every three to four years. WeExpand
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A stereological study of glomerular number and volume: preliminary findings in a multiracial study of kidneys at autopsy.
BACKGROUND This report describes preliminary results of a study of glomerular number and volume and their associations, in kidneys of people coming to autopsy. METHODS Both kidneys were weighed atExpand
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Hypertension, glomerular number, and birth weight in African Americans and white subjects in the southeastern United States.
Low nephron number has been related to low birth weight and hypertension. In the southeastern United States, the estimated prevalence of chronic kidney disease due to hypertension is five timesExpand
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Post-streptococcal glomerulonephritis is a strong risk factor for chronic kidney disease in later life.
Although unusual in western countries and in Australia in general, post-streptococcal glomerulonephritis (PSGN) is still common in Australian Aboriginal children living in remote communities. Here,Expand
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