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Influence of 100% and 40% Oxygen on Penumbral Blood Flow, Oxygen Level, and T*2-Weighted MRI in a Rat Stroke Model
For diagnostic imaging, 40% O2 OC could provide sufficient T*2 signal change to detect penumbra with limited influence in BP and CBF and determined the effects on blood pressure, CBF, tissue pO2, and T*1 signal change in presumed penumbr in a rat stroke model. Expand
Potential use of Oxygen as a Metabolic Biosensor in Combination with T2*-Weighted MRI to Define the Ischemic Penumbra
A novel magnetic resonance imaging technique for detecting metabolism indirectly through changes in oxyhemoglobin:deoxyhemoglobin ratios and T2* signal change during ‘oxygen challenge’ (OC) has potential clinical utility and, by distinguishing metabolically active and inactive tissues within hypoperfused regions, could provide a more precise assessment of penumbra. Expand
Rheo-NMR phenomena of wormlike micelles.
Using a combination of rheology and nuclear magnetic resonance (NMR) spectroscopy/velocimetry, the existence of shear banding fluctuations under Couette flow of the micellar system is demonstrated and direct measurement of the shear-induced nematic phase transition is reported. Expand
In ovo non‐invasive quantification of the myocardial function and mass of chick embryos using magnetic resonance imaging
The use of retrospective Cine MRI is presented to measure the cardiac function of chick embryos in ovo for the first time, without the need for respiratory or cardiac gating. Expand
A new approach to define surface/sub-surface transition in gravel beds
The vertical structure of river beds varies temporally and spatially in response to hydraulic regime, sediment mobility, grain size distribution and faunal interaction. Implicit are changes to theExpand
Intracranial Pressure Elevation after Ischemic Stroke in Rats: Cerebral Edema is Not the Only Cause, and Short-Duration Mild Hypothermia is a Highly Effective Preventive Therapy
It is suggested that factors other than cerebral edema are the primary cause of the ICP elevation 24 hours after stroke onset, and short-duration mild or moderate hypothermia prevented this rise. Expand
Shear banding fluctuations and nematic order in wormlike micelles.
Using rapid NMR velocimetry, deuterium NMR shows that the onset of shear banding is associated with a nematic micellar state whose order parameter depends on shear rate. Expand
Fgfr3 regulates development of the caudal telencephalon
The results indicate the subtle role of Fgfr3 in formation of caudal regions of the telencephalon affecting some brain projections, as well as a subtle thalamocortical tract deficit, detected by dye‐tracing and diffusion magnetic resonance imaging and tractography. Expand
Magnetic Resonance Imaging of Structure, Diffusivity, and Copper Immobilization in a Phototrophic Biofilm
MRI and reaction transport models are versatile tools which can significantly improve the understanding of heavy metal immobilization in naturally occurring biofilms. Expand
T2*‐weighted magnetic resonance imaging with hyperoxia in acute ischemic stroke
We describe the first clinical application of transient hyperoxia (“oxygen challenge”) during T2*‐weighted magnetic resonance imaging (MRI), to detect differences in vascular deoxyhemoglobin betweenExpand