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Asymmetric hydrogenation of isobutyrophenone using a [(Diphosphine) RuCl2 (1,4-diamine)] catalyst.
[reaction: see text] The use of three chiral 1,4-diamines in the [(diphosphine) RuCl(2) (diamine)] catalyst system is demonstrated in the hydrogenation of acetophenone. The use of a 1,4-diamineExpand
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Synthesis of Highly Cross-Linked Polymers in Supercritical Carbon Dioxide by Heterogeneous Polymerization
This paper reports the synthesis of highly cross-linked polymers in supercritical CO2 (scCO2), both with and without the addition of a CO2-soluble diblock copolymer stabilizer. It was demonstratedExpand
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Asymmetric hydrogenation using chiral Rh complexes immobilised with a new ion-exchange strategy.
Rh diphosphine complexes using DuPhos and JosiPhos as chiral ligands have been immobilised by ion exchange into the mesoporous material MCM-41. When used as catalysts for the enantioselectiveExpand
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Studies on the preparation of camphorylidene derivatives of α-amino acids
An improved method has been developed for the efficient synthesis of stable camphor imine salts. Camphor imine readily undergoes transimination with α-amino acid ester hydrochlorides to yieldExpand
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Accelerated asymmetric transfer hydrogenation of aromatic ketones in water.
Asymmetric transfer hydrogenation of various simple aromatic ketones by the Ru-TsDPEN catalyst was shown to be feasible in aqueous HCOONa without calling for any catalyst modification, furnishingExpand
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A Catalyst for Efficient and Highly Enantioselective Hydrogenation of Aromatic, Heteroaromatic, and α,β-Unsaturated Ketones
PhanePhos−ruthenium−diamine complexes catalyze the asymmetric hydrogenation of a wide range of aromatic, heteroaromatic, and α,β-unsaturated ketones with high activity and excellentExpand
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[(Bisphosphine) Ru(II) diamine] complexes in asymmetric hydrogenation: expanding the scope of the diamine ligand.
[(Bisphosphine) RuCl 2 (1,2-diamine)] complexes are powerful catalysts in the asymmetric hydrogenation of unfunctionalized ketones. We sought to expand the scope and applicability of these complexesExpand
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Carbohydrate-derived amino-alcohol ligands for asymmetric alkynylation of aldehydes.
[reaction: see text] Conformationally restricted amino alcohols based on carbohydrate scaffolds provide flexible and fine-tuneable libraries that greatly expand the range of ligands available in theExpand
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Practical Asymmetric Synthesis of (+)-erythro Mefloquine Hydrochloride
A highly enantioselective and cost efficient process for the synthesis of (+)-erythro mefloquine has been developed. The key step is an enantioselective reduction of pyridyl ketone KI using transferExpand
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Ruthenium-Catalysed Asymmetric Reduction of Ketones
ketones is a reaction of particular importance to the pharmaceutical industry. In the 1980s, research by Professor Ryoji Noyori’s group at Nagoya University in Japan, on BINAP-ruthenium catalystsExpand
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