• Publications
  • Influence
HCN and chemical evolution: the possible role of cyano compounds in prebiotic synthesis.
Synthese et distribution de HCN. Autocondensation de HCN: obtention de nitriles ou de liants oligomeres. Role possible des composes cyano comme agents de condensation
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Montmorillonite: A multifunctional mineral catalyst for the prebiological formation of phosphate esters
Reaction of diiminosuccinonitrile (DISN) with 3′-AMP in the presence of alkali- and alkaline earth-montmorillonites results in the formation of 2′,3′-cAMP in aqueous solution. Little or no 2′,3′-cAMPExpand
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N-cyanoimidazole and diimidazole imine: water-soluble condensing agents for the formation of the phosphodiester bond.
The reaction of BrCN with imidazole results in the formation of N-cyanoimidazole and diimidazole imine. These compounds were shown to be useful condensing agents for the formation of theExpand
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The adsorption and reaction of adenine nucleotides on montmorillonite
  • J. Ferris, W. Hagan
  • Chemistry, Medicine
  • Origins of life and evolution of the biosphere
  • 1 March 1986
The binding of AMP to Zn2+-montmorillonite was investigated in the presence of buffers and salts. Good's buffers, piperazine-N,N′-bis(2-ethanesulfonate) [PIPES] and morpholine-N-2-ethanesulfonateExpand
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The investigation of the hcn derivative diiminosuccinonitrile as a prebiotic condensing agent. The formation of phosphate esters
Diiminosuccinonitrile (DISN) is formed readily by the Fe3+ oxidation of diaminomaleonitrile, a tetramer of HCN. DISN effects the phosphorylation of uridine in 13% yield to a mixture of the isomers ofExpand
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Picket-fence porphyrins as potential phototherapeutic agents.
The synthetic "picket fence" porphyrin, tetra(o-acetamidophenyl)porphine (TAc), as a biological photosensitizer has been evaluated both in vitro and in vivo in mitochondria from the R3230AC mammaryExpand
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Chemical evolution 40. clay-mediated oxidation of diaminomaleonitrile
SummaryThe previously reported inhibition of the oligomerization of HCN by montmorillonite clays was investigated. The inhibition is due to the oxidation of diaminomaleonitrile (DAMN) by the Fe3+ inExpand
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Prebiotic synthesis and reactions of nucleosides and nucleotides.
Diiminosuccinonitrile (DISN) has been investigated as a potential prebiotic phosphorylating agent. It is formed readily by the oxidation of diaminomaleonitrile (DAMN), a tetramer of HCN. DISN effectsExpand
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SYNTHETIC PORPHYRINS AT INTERFACES; PHOTOSENSITIZATION AND RELATED REACTIONS OF ATROPISOMERS OF o‐SUBSTITUTED TETRAPHENYLPORPHINE DERIVATIVES IN FILMS, REVERSED MICELLES AND MEMBRANES †
Abstract— Previous studies from our laboratories and elsewhere have shown that amides between fatty acids and the synthetic α, α, α, α ‐tetra (o‐aminophenyl)‐porphyrins exhibit good surfactantExpand
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