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ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue
We describe a clearing method for enhanced visualization of cell morphology and connections in neuronal and non-neuronal tissue. Using ClearT or ClearT2, which are composed of formamide orExpand
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Burst and tonic response modes in thalamic neurons during sleep and wakefulness.
Thalamic neurons can exhibit two distinct firing modes: tonic and burst. In the lateral geniculate nucleus (LGN), the tonic mode appears as a relatively faithful relay of visual information fromExpand
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Structural and functional composition of the developing retinogeniculate pathway in the mouse.
The advent of transgenic mice has made the developing retinogeniculate pathway a model system for targeting potential mechanisms that underlie the refinement of sensory connections. However, aExpand
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Failure to Maintain Eye-Specific Segregation in nob, a Mutant with Abnormally Patterned Retinal Activity
Axon terminals from the two eyes initially overlap in the dorsal-lateral geniculate nucleus (dLGN) but subsequently refine to occupy nonoverlapping territories. Retinal activity is required toExpand
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Morphologically Distinct Classes of Relay Cells Exhibit Regional Preferences in the Dorsal Lateral Geniculate Nucleus of the Mouse
A fundamental feature of the mammalian visual system is the presence of separate channels that work in parallel to efficiently extract and analyze specific elements of a visual scene. Despite theExpand
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Burst responses in thalamic relay cells of the awake behaving cat.
1. Relay cells of the dorsal lateral geniculate nucleus (LGN) respond in one of two modes: tonic or burst. The purpose of this study was to determine whether, and under what conditions, burstExpand
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Loss of binocular responses and reduced retinal convergence during the period of retinogeniculate axon segregation.
In the developing mammalian visual system, axon terminals from the two eyes overlap in the dorsal lateral geniculate nucleus (LGN) but then undergo a period of refinement and segregate to formExpand
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Neurofilament Proteins in Y-Cells of the Cat Lateral Geniculate Nucleus: Normal Expression and Alteration with Visual Deprivation
We examined neurofilament staining in the normal and visually deprived lateral geniculate nucleus (LGN), using the SMI-32 antibody. This antibody preferentially stains LGN cells that display theExpand
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Synaptic development of the mouse dorsal lateral geniculate nucleus
The dorsal lateral geniculate nucleus (dLGN) of the mouse has emerged as a model system in the study of thalamic circuit development. However, there is still a lack of information regarding how andExpand
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Retinal Input Regulates the Timing of Corticogeniculate Innervation
Neurons in layer VI of visual cortex represent one of the largest sources of nonretinal input to the dorsal lateral geniculate nucleus (dLGN) and play a major role in modulating the gain of thalamicExpand
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