W. Geraerts

Publications132
h-index46
Citations6,202
Highly Influential Citations174
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A glia-derived acetylcholine-binding protein that modulates synaptic transmission
TLDR
A molecular and cellular mechanism by which glial cells release AChBP in the synaptic cleft is described, and a model for how they actively regulate cholinergic transmission between neurons in the central nervous system is proposed.
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Towards Understanding the Role of Insulin in the Brain: Lessons from Insulin-related Signaling Systems in the Invertebrate Brain
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Molecular cloning and characterization of an invertebrate homologue of a neuropeptide Y receptor
TLDR
The cloning of a neuropeptide Y‐receptor from the brain of the snail Lymnaea stagnalis is described, and an active peptide was purified to homogeneity, analysed by mass spectrometry and amino acid sequence determination, and turned out to be a LymNAea homologue of neuropeptic Y.
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The sorLA cytoplasmic domain interacts with GGA1 and ‐2 and defines minimum requirements for GGA binding
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Functional Implications of Neurotransmitter Expression during Axonal Regeneration: Serotonin, But Not Peptides, Auto-Regulate Axon Growth of an Identified Central Neuron
TLDR
The data suggest that auto-released serotonin is inhibitory to CGC neurite outgrowth in vitro, and during regeneration in vivo, serotonin release might fine-tune axon guidance and branching by inducing local collapse responses in extending neurites.
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A novel G protein-coupled receptor mediating both vasopressin- and oxytocin-like functions of Lys-conopressin in Lymnaea stagnalis
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Cloning, Characterization, and Expression of a G-Protein-Coupled Receptor from Lymnaea stagnalis and Identification of a Leucokinin-Like Peptide, PSFHSWSamide, as Its Endogenous Ligand
TLDR
This Lymnaeareceptor, PSFHSWSamide, is the first example of a leucokinin-like neuropeptide receptor, representing a new subfamily of G-protein-coupled neuropePTide receptors.
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Molluscan putative prohormore convertases: Structural diversity in the central nervous system of Lymnaea stagnalis
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Synthesis and functional integration of a neurotransmitter receptor in isolated invertebrate axons.
TLDR
This study provides the first direct evidence that isolated axons (in the absence of the soma) can intrinsically synthesize and functionally integrate a membrane-bound receptor protein from an axonally injected mRNA.
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Control of growth by the neurosecretory hormone of the light green cells in the freshwater snail Lymnaea stagnalis.
  • W. Geraerts
  • Biology, Medicine
    General and comparative endocrinology
  • 1 May 1976
View on PubMed
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