• Publications
  • Influence
Structures of synthetic polynucleotides in the A-RNA and A'-RNA conformations: x-ray diffraction analyses of the molecular conformations of polyadenylic acid--polyuridylic acid and polyinosinic
TLDR
Since homopolymer stretches in DNA appear to act as control sites for RNA transcription, the possible enhanced stability of their A conformations is consistent with a suggestion that DNA might adopt the A conformation during transcription.
Stereochemistry of intercalation: interaction of daunomycin with DNA.
TLDR
Daunomycin, a glycosidic anthracycline antibiotic from Streptomyces peucetius, is being used in the treatment of acute leukaemia and solid tumours in man due to complex formation with the DNA of deoxyribonucleoprotein4.
THE MOLECULAR CONFIGURATION OF DEOXYRIBONUCLEIC ACID. IV. X-RAY DIFFRACTION STUDY OF THE A FORM.
TLDR
Detailed three-dimensional X-ray diffraction data from microcrystalline fibres of the sodium salt of DNA are described, confirming the correctness of the Watson-Crick scheme for base-pairing and eliminating the possibility that DNA molecules might have a left-handed configuration.
Time resolved study of oriented crystallisation of poly(lactic acid) during rapid tensile deformation
Abstract Poly( l -lactic acid) with 4% d -lactic acid comonomer has been drawn in the amorphous state at 80, 90, 100, 110 and 120 °C at an extension rate of 4 s−1 while simultaneously recording WAXS
Observation of a transient structure prior to strain-induced crystallization in poly(ethylene terephthalate)
Abstract Using time-resolved X-ray diffraction at the European Synchrotron Radiation Facility we have observed a highly oriented weak transient diffraction peak which persists for about 0.2 s prior
A Molecular Model for the Interaction of Ethidium Bromide with Deoxyribonucleic Acid
X-ray diffraction and molecular model building studies have led to a model for the interaction between deoxyribonucleic acid (DNA) and ethidium bromide in which the planar ring system of the drug is
Molecular Conformations and Structure Transitions of RNA Complementary Helices and their Possible Biological Significance
RNA can exist in three distinct forms, all with a similar structure to that of the A form of DNA. The possible biological significance of these structures in protein synthesis and transcription
Influence of temperature and chain orientation on the crystallization of poly(ethylene terephthalate) during fast drawing
Abstract Three regimes of poly(ethylene terephthalate) (PET) deformation are identified from a detailed analysis of time-resolved wide angle X-ray scattering (WAXS) data recorded during the
...
1
2
3
4
5
...