• Publications
  • Influence
Toward Defining the Course of Evolution: Minimum Change for a Specific Tree Topology
Fitch, W. M. (Dept. of Physiological Chemistry, Univ. of Wisconsin, Madison, Wisconsin, 53706), 1971. Toward defining the course of evolution: minimum change for a specific tree topology. Syst.Expand
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Construction of phylogenetic trees.
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Tempo and mode in evolution.
  • W. Fitch, F. Ayala
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 19 July 1994
George Gaylord Simpson said in his classic Tempo and Mode in Evolution (1) that paleontologists enjoy special advantages over geneticists on two evolutionary topics. One general topic, suggested byExpand
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Distinguishing homologous from analogous proteins.
  • W. Fitch
  • Biology, Medicine
  • Systematic zoology
  • 1 June 1970
Fitch, W. M. (Dept. Physiological Chem., U. Wisconsin, Madison 53706) 1970. Distinguishing homologous from analogaus proteins. Syst. Zool., 19:99-113.-This work provides a means by which it isExpand
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A natural classification of the basic helix-loop-helix class of transcription factors.
  • W. Atchley, W. Fitch
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 13 May 1997
A natural (evolutionary) classification is provided for 242 basic helix-loop-helix (bHLH) motif-containing proteins. Phylogenetic analyses of amino acid sequences describe the patterns ofExpand
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Homology a personal view on some of the problems.
  • W. Fitch
  • Biology, Medicine
  • Trends in genetics : TIG
  • 1 May 2000
There are many problems relating to defining the terminology used to describe various biological relationships and getting agreement on which definitions are best. Here, I examine 15 terminologicalExpand
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Long term trends in the evolution of H(3) HA1 human influenza type A.
We have studied the HA1 domain of 254 human influenza A(H3N2) virus genes for clues that might help identify characteristics of hemagglutinins (HAs) of circulating strains that are predictive of thatExpand
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On the Problem of Discovering the Most Parsimonious Tree
  • W. Fitch
  • Biology
  • The American Naturalist
  • 1 March 1977
The problem of discovering the most parsimonious tree is defined in terms of a set of linearly arrayed sequences. Simplifications are introduced to reduce the total amount of work including theExpand
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We assessed the utility of congruence and multiple data sets to test species relationships and the accuracy of phylogenetic methods. The ongoing controversy about whether to combine data sets forExpand
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Nucleotide sequence and genomic organization of feline immunodeficiency virus.
An infectious molecular clone of the Petaluma strain of feline immunodeficiency virus (FIV) was isolated from a recombinant bacteriophage library containing genomic DNA prepared from FIV-infectedExpand
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