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An optical coherence tomography-guided, variable dosing regimen with intravitreal ranibizumab (Lucentis) for neovascular age-related macular degeneration.
OCT appears useful for determining when retreatment with ranibizumab is necessary, and resulted in visual acuity outcomes similar to the Phase III clinical studies, but required fewer intravitreal injections. Expand
A variable-dosing regimen with intravitreal ranibizumab for neovascular age-related macular degeneration: year 2 of the PrONTO Study.
The PrONTO Study using an OCT-guided variable-dosing regimen with intravitreal ranibizumab resulted in VA outcomes comparable with the outcomes from the phase III clinical studies, but fewer intravItreal injections were required. Expand
Evaluation of Subjective Assessments and Objective Diagnostic Tests for Diagnosing Tear‐Film Disorders Known to Cause Ocular Irritation
Purpose To determine which subjective assessments and objective tests have clinical utility as diagnostic tools in ocular irritation associated with Sjögren's syndrome—related aqueous tear deficiencyExpand
Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years.
Gene therapy for Leber congenital amaurosis caused by RPE65 mutations is sufficiently safe and substantially efficacious in the extrafoveal retina and the results point to specific treatment strategies for subsequent phases. Expand
Treatment outcomes in the Tube Versus Trabeculectomy (TVT) study after five years of follow-up.
Tube shunt surgery had a higher success rate compared to trabeculectomy with MMC during 5 years of follow-up in the TVT Study and both procedures were associated with similar IOP reduction and use of supplemental medical therapy at 5 years. Expand
Long-term outcome of keratolimbal allograft with or without penetrating keratoplasty for total limbal stem cell deficiency.
Ambulatory vision for a period of more than 2 years can be achieved by KLAL with or without PKP in eyes with severe ocular surface disorders caused by total LSCD, however, a progressive decline of the visual outcome and graft survival is evident with time. Expand
Quality of life of low-vision patients and the impact of low-vision services.
The SF-36, VF-14, and NEI-VFQ demonstrate that low-vision clinic patients perceive marked impairment of functional status and quality of life and are associated with high patient satisfaction. Expand
Quantitative assessment of atypical birefringence images using scanning laser polarimetry with variable corneal compensation.
ABP images exist in a subset of normal and glaucomatous eyes, are associated with older patient age, and produce an artifactual increase in RNFL thickness using GDx-VCC. Expand
Postoperative complications in the Tube Versus Trabeculectomy (TVT) study during five years of follow-up.
The rates of late postoperative complications, reoperation for complications, and cataract extraction were similar with both surgical procedures after 5 years of follow-up, and a large number of surgical complications were observed. Expand
Visual function and quality of life among patients with glaucoma.
Based on the moderate correlation between binocular visual field impairment with the VF-14 and the National Eye Institute-Visual Functioning Questionnaire, these questionnaires may be useful among patients with glaucoma. Expand