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Analysis of a chemical plant defense mechanism in grasses.
In the Gramineae, the cyclic hydroxamic acids 2,4-dihydroxy-1, 4-benzoxazin-3-one (DIBOA) and 2,4-dihydroxy-7-methoxy-1, 4-benzoxazin-3-one (DIMBOA) form part of the defense against insects andExpand
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Deoxyxylulose phosphate pathway to terpenoids.
Recently, a mevalonate-independent pathway was discovered in bacteria and plants that leads to the formation of isopentenyl diphosphate and dimethylallyl diphosphate, the two basic precursors ofExpand
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Bacterial phenylalanine and phenylacetate catabolic pathway revealed
Aromatic compounds constitute the second most abundant class of organic substrates and environmental pollutants, a substantial part of which (e.g., phenylalanine or styrene) is metabolized byExpand
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A dicarboxylate/4-hydroxybutyrate autotrophic carbon assimilation cycle in the hyperthermophilic Archaeum Ignicoccus hospitalis
Ignicoccus hospitalis is an anaerobic, autotrophic, hyperthermophilic Archaeum that serves as a host for the symbiotic/parasitic Archaeum Nanoarchaeum equitans. It uses a yet unsolved autotrophic CO2Expand
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The deoxyxylulose phosphate pathway of terpenoid biosynthesis in plants and microorganisms.
Recent studies have uncovered the existence of an alternative, non-mevalonate pathway for the formation of isopentenyl pyrophosphate and dimethylallyl pyrophosphate, the two building blocks ofExpand
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Systematics of 2H patterns in natural compounds and its importance for the elucidation of biosynthetic pathways
The relative global 2H-content of natural plant products is correlated to that of the primary hydrogen source, i.e. water, to the site of their biosynthesis (C3-, C4- and CAM-plants; chloroplasts,Expand
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The deoxyxylulose phosphate pathway of isoprenoid biosynthesis: Studies on the mechanisms of the reactions catalyzed by IspG and IspH protein
Earlier in vivo studies have shown that the sequential action of the IspG and IspH proteins is essential for the reductive transformation of 2C-methyl-d-erythritol 2,4-cyclodiphosphate intoExpand
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Studies on the nonmevalonate terpene biosynthetic pathway: Metabolic role of IspH (LytB) protein
Isopentenyl diphosphate and dimethylallyl diphosphate serve as the universal precursors for the biosynthesis of terpenes. Although their biosynthesis by means of mevalonate has been studied inExpand
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Carbon metabolism of Listeria monocytogenes growing inside macrophages
The intracellular metabolism of Listeria monocytogenes was studied by 13C‐isotopologue profiling using murine J774A.1 macrophages as host cells. Six hours after infection, bacteria were separatedExpand
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Probing the reaction mechanism of IspH protein by x-ray structure analysis
Isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) represent the two central intermediates in the biosynthesis of isoprenoids. The recently discovered deoxyxylulose 5-phosphateExpand
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