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LINC02273 drives breast cancer metastasis by epigenetically increasing AGR2 transcription
A novel long noncoding RNA LINC02273, whose expression was significantly elevated in metastatic lesions compared to the primary tumors, was identified by genetic screen of matched tumor samples and revealed that L INC02273-targeting antisense oligonucleotides (ASO) substantially inhibited breast cancer metastasis in vivo.
Increased Mortality with Repeat Lumpectomy Alone After Ipsilateral Breast Tumor Recurrence.
The investigation suggests that compared with mastectomy, repeat lumpectomy for IBTR is associated with higher overall and cancer-specific mortality under real-world observational conditions, and repeat Lumpectomy with RT is equivalent to mastectomy with respect to overall mortality and may influence treatment decision making for patients with small IBTR.
Changing patterns and survival improvements of young breast cancer in China and SEER database, 1999−2017
There has been a substantial de-escalation in surgical therapies in young breast cancer patients and both the FUSCC and SEER cohorts showed a significantly better prognosis in the recent time period.
Comparison of prepectoral and subpectoral breast reconstruction after mastectomies: A systematic review and meta analysis.
A nomogram for predicting axillary pathologic complete response in hormone receptor–positive breast cancer with cytologically proven axillary lymph node metastases
The objective of this study was to determine an axillary pathologic complete response (pCR) and its influencing factors in patients with hormone receptor (HR)–positive breast cancer and cytologically…
Current practice and barriers of mesh-assisted implant-based breast reconstruction in China: A nationwide cross-sectional survey of 110 hospitals.
Applications of rib sparing technique in internal mammary vessels exposure of abdominal free flap breast reconstructions: a 12-year single-center experience of 215 cases.
IMVs were used more frequently as the recipient vessels in abdominal free flap breast reconstructions, especially when axillary operation was not performed at the same time, and rib sparing technique had the potential to decrease surgery time, hospitalization days and complications rate.
LINC00309 is associated with short disease-free survival in breast cancer
In breast cancer, LINC00309 is significantly associated with poor prognosis and may represent a new marker of prognosis.
High expression of Linc00959 predicts poor prognosis in breast cancer
Examination of the expression pattern of Linc00959 in BC revealed its biological role and clinical significance in prediction of prognosis and its survival analysis showed it served as an independent prognostic marker in breast cancer.
[Current practice of implant-based breast reconstruction: results from China national practice questionnaire survey].
IBBR was the most common used surgery in breast reconstruction after mastectomy in China, however, the proportion of IBBR in patients aftermastectomy was still low andReginal economy, surgery volume of hospitals, lack of specialty training program and the concern about complications and patient's satisfaction were the factors affecting the development ofIBBR.