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Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells
It is shown that human fetal and adult fibroblast feeders support prolonged undifferentiated HES cell growth of existing cell lines and are superior to cell-free matrices supplemented with human or MEF feeder–conditioned medium. Expand
The Transcriptome Profile of Human Embryonic Stem Cells as Defined by SAGE
The overlapping similarities and differences in gene expression profiles of human and mouse ES cells provide a foundation for a detailed and concerted dissection of the molecular and cellular mechanisms governing their pluripotency, directed differentiation into specific cell types, and extended ability for self‐renewal. Expand
Thyroid hormones are important for embryonic to larval transitory phase in zebrafish.
  • Yi-Wen Liu, W. Chan
  • Biology, Medicine
  • Differentiation; research in biological diversity
  • 1 March 2002
It is proposed that the embryonic to larval transitory phase in many teleost species is characterized by its dependency on the timely synthesis of TH and the concomitant autoinductive increase in TR beta mRNA levels. Expand
Comparative Evaluation of Various Human Feeders for Prolonged Undifferentiated Growth of Human Embryonic Stem Cells
It is reported that two adult skin fibroblast cell lines established in‐house from abdominal skin biopsies supported prolonged undifferentiated hES cell growth for over 30 weekly passages in culture. Expand
Human Wharton’s Jelly Stem Cells Have Unique Transcriptome Profiles Compared to Human Embryonic Stem Cells and Other Mesenchymal Stem Cells
The ability to modulate immune responses makes hWJSCs an important compatible stem cell source for transplantation therapy in allogeneic settings without immunorejection and provides a foundation for future functional studies where the exact mechanisms of these unique properties of hW JSCs can be confirmed. Expand
Effect of preparation conditions on morphology and release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion method
Abstract We have investigated the key parameters to fabricate PDLLA (Poly( dl -lactic acid)), PDLLGA (Poly( dl -lactic-co-glycolic acid) 65 : 35 and blends of PDLLGA 65 : 35 and PEG (Poly(ethyleneExpand
Invasion success and genetic diversity of introduced populations of guppies Poecilia reticulata in Australia
Success of invasion of Australia and high additive genetic variance in Australian guppies are not associated with high levels of diversity at molecular loci, consistent with the release of additive genetic variation by dominance and epistasis following inbreeding, and with disruptive and negative frequency‐dependent selection on fitness traits. Expand
An Efficient and Safe Xeno‐Free Cryopreservation Method for the Storage of Human Embryonic Stem Cells
The cryopreservation technique described here should complement xeno‐free culture conditions for hESCs already in refinement and will prove very useful for the setting up of hESC banks throughout the world. Expand
Ff1b is required for the development of steroidogenic component of the zebrafish interrenal organ.
It is proposed that ff1b is required for the development of the steroidogenic tissue of the interrenal organ in zebrafish and could be mimicked by treatment with aminoglutethimide, an inhibitor of de novo steroid synthesis. Expand