• Publications
  • Influence
Air Pollution and Cardiovascular Disease: A Statement for Healthcare Professionals From the Expert Panel on Population and Prevention Science of the American Heart Association
Air pollution is a heterogeneous, complex mixture of gases, liquids, and particulate matter. Epidemiological studies have demonstrated a consistent increased risk for cardiovascular events inExpand
  • 1,910
  • 85
  • PDF
The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy.
Using confocal microscopy, onset of the mitochondrial permeability transition (MPT) in individual mitochondria within living cells can be visualized by the redistribution of the cytosolicExpand
  • 1,343
  • 47
Particulate matter exposure in cars is associated with cardiovascular effects in healthy young men.
Exposure to fine airborne particulate matter (PM(2.5)) is associated with cardiovascular events and mortality in older and cardiac patients. Potential physiologic effects of in-vehicle, roadside, andExpand
  • 439
  • 29
  • PDF
Elderly humans exposed to concentrated air pollution particles have decreased heart rate variability
Air pollution particles are thought to kill >500,000 people worldwide each year. The population most at risk appears to be elderly people with respiratory and cardiovascular disease. As yet, noExpand
  • 310
  • 18
Concentrated ambient ultrafine particle exposure induces cardiac changes in young healthy volunteers.
RATIONALE Exposure to ambient ultrafine particles has been associated with cardiopulmonary toxicity and mortality. Adverse effects specifically linked to ultrafine particles include loss ofExpand
  • 150
  • 13
Cardiovascular effects in patrol officers are associated with fine particulate matter from brake wear and engine emissions
BackgroundExposure to fine particulate matter air pollutants (PM2.5) affects heart rate variability parameters, and levels of serum proteins associated with inflammation, hemostasis and thrombosis.Expand
  • 142
  • 12
Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy.
Inhibition of mitochondrial oxidative phosphorylation progresses to uncoupling when opening of cyclosporin A-sensitive permeability transition pores increases permeability of the mitochondrial innerExpand
  • 306
  • 11
Mitochondrial Dysfunction in the Pathogenesis of Necrotic and Apoptotic Cell Death
Mitochondria are frequently the target of injury after stresses leading to necrotic and apoptoticcell death. Inhibition of oxidative phosphorylation progresses to uncoupling when opening ofa highExpand
  • 379
  • 10
Endothelial Dysfunction: Associations with Exposure to Ambient Fine Particles in Diabetic Individuals
Background Exposure to fine airborne particulate matter [≤2.5 μm in aerodynamic diameter (PM2.5)] has been associated with cardiovascular and hematologic effects, especially in older people withExpand
  • 116
  • 10
Peat Bog Wildfire Smoke Exposure in Rural North Carolina Is Associated with Cardiopulmonary Emergency Department Visits Assessed through Syndromic Surveillance
Background: In June 2008, burning peat deposits produced haze and air pollution far in excess of National Ambient Air Quality Standards, encroaching on rural communities of eastern North Carolina.Expand
  • 192
  • 10
  • PDF