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Cell polyploidy: its relation to tissue growth and function.
This chapter discusses the cell polyploidy and its relation to tissue growth and function and the mechanism of supplanting mitotic syntheses by tissue-specific ones as the cause of reduction in the stages of mitosis may be common for different cell populations. Expand
Mitotic-cyclic and cycle-independent growth of cardiomyocytes.
- W. Brodsky, N. N. Tsirekidze, A. Arefyeva
- Biology, Medicine
- Journal of molecular and cellular cardiology
- 1 May 1985
The number of myocytes in mouse heart ventricles increased by 25% to 30%, on average, mainly for 3 days after birth, and it was assumed that the water content and the non-muscle component of myocardium varied from heart to heart. Expand
Protein synthesis rhythm.
- W. Brodsky
- 1 November 1975
The existence of functional adaptations of protein synthesis rhythm is found and some evidence for cellular “memory” in this process is obtained, suggesting that this periodicity reflects the existence of a rhythm ofprotein synthesis. Expand
Mitotic polyploidization of mouse heart myocytes during the first postnatal week
It is concluded that cell multiplication is practically arrested at this period of life, and growth of the ventricular mass is due to polyploidization of virtually all cycling cells, while their number remains unchanged. Expand
DNA synthesis in the Purkinje neurons.
- W. Brodsky, T. Marshak, Z. Mikeladze, G. N. Moskovkin, M. K. Sadykova
- Chemistry, Medicine
- Basic and applied histochemistry
Control estimations with deoxyribonuclease, hot perchloric acid and covering the autoradiographs established that the Purkinje cells synthesize DNA perhaps for the purpose of DNA surplus accumulation and/or DNA repair in the neurons. Expand
Kinetics of cellular proliferation in regenerating mouse liver pretreated with the alkylating drug dipin
- V. Faktor, I. V. Uryvaeva, A. Sokolova, V. Chernov, W. Brodsky
- Biology, Medicine
- Virchows Archiv. B, Cell pathology including…
Pretreatment of resting liver with Dipin altered the kinetics of cell proliferation following partial hepatectomy, resulting in delay in division resulted primarily from an increase in the DNA-synthesis time and a prolonged block of the transition from G2 to mitosis. Expand
A cytophotometric and karyometric study of the cardiac muscle cells of young rats exposed to intermittent high altitude hypoxia.
The data indicate enhancement of mitotic division of mono- and binuclear diploid cells in hypoxic animals and an increase in mononuclear and bin nuclear tetraploids cells occurred. Expand
Dry weight and 5HT concentration in the cerebral ganglia of Anodonta (Mollusca) during activity.
- A. Arefyeva, J. Nemcsók, J. Salánki, W. Brodsky
- Medicine, Biology
- Acta biologica Academiae Scientiarum Hungaricae
The amount of serotonin in cerebral ganglia changes independently of the amount of protein in nerve cells, although it varies consistently with the activity and rest of the animal. Expand