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Acute Kidney Injury After Cardiac Surgery: Focus on Modifiable Risk Factors
Background— Acute kidney injury (AKI) after cardiac surgery is a major health issue. Lacking effective therapies, risk factor modification may offer a means of preventing this complication. TheExpand
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Aspirin “resistance” and risk of cardiovascular morbidity: systematic review and meta-analysis
Objective To determine if there is a relation between aspirin “resistance” and clinical outcomes in patients with cardiovascular disease. Design Systematic review and meta-analysis. Data sourceExpand
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Derivation and validation of a simplified predictive index for renal replacement therapy after cardiac surgery.
CONTEXT A predictive index for renal replacement therapy (RRT; hemodialysis or continuous venovenous hemodiafiltration) after cardiac surgery may improve clinical decision making and research design.Expand
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Preoperative Use of Statins Is Associated with Reduced Early Delirium Rates after Cardiac Surgery
Background:Delirium is an acute deterioration of brain function characterized by fluctuating consciousness and an inability to maintain attention. Use of statins has been shown to decrease morbidityExpand
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Off-pump coronary artery surgery for reducing mortality and morbidity: meta-analysis of randomized and observational studies.
OBJECTIVES The purpose of this study was to assess the effects of off-pump coronary bypass surgery (OPCAB) on mortality and morbidity. BACKGROUND Despite its potential for reducing morbidity andExpand
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How strong is the evidence for the use of perioperative β blockers in non-cardiac surgery? Systematic review and meta-analysis of randomised controlled trials
Abstract Objective To determine the effect of perioperative β blocker treatment in patients having non-cardiac surgery. Design Systematic review and meta-analysis. Data sources Seven searchExpand
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Continuous Intravenous Administration of Ketorolac Reduces Pain and Morphine Consumption After Total Hip or Knee Arthroplasty
The purpose of this study was to determine the analgesic efficacy, opioid-sparing effect, and tolerability of ketorolac administered as an intravenous (IV) bolus followed by a continuous infusionExpand
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Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications: a meta-analysis.
PURPOSE To investigate the effects of alpha(2)-adrenergic agonists on perioperative mortality and cardiovascular complications in adults undergoing surgery. METHODS MEDLINE (1966 to May 2002),Expand
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Recombinant factor VIIa for intractable blood loss after cardiac surgery: a propensity score-matched case-control analysis.
BACKGROUND Cardiac surgery is occasionally complicated by massive blood loss that is refractory to standard hemostatic interventions. Recombinant factor VIIa (rF-VIIa) is being increasingly used asExpand
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Perioperative Myocardial Infarction
More than 230 million major surgeries are performed annually worldwide,1 and this number grows continuously. The 30-day mortality associated with moderate- to high-risk noncardiac surgery in recentExpand
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