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Acute Kidney Injury After Cardiac Surgery: Focus on Modifiable Risk Factors
Background— Acute kidney injury (AKI) after cardiac surgery is a major health issue. Lacking effective therapies, risk factor modification may offer a means of preventing this complication. The… Expand
Aspirin “resistance” and risk of cardiovascular morbidity: systematic review and meta-analysis
- G. Krasopoulos, S. Brister, W. Beattie, M. D. Buchanan
- BMJ : British Medical Journal
- 17 January 2008
Objective To determine if there is a relation between aspirin “resistance” and clinical outcomes in patients with cardiovascular disease. Design Systematic review and meta-analysis. Data source… Expand
Derivation and validation of a simplified predictive index for renal replacement therapy after cardiac surgery.
CONTEXT A predictive index for renal replacement therapy (RRT; hemodialysis or continuous venovenous hemodiafiltration) after cardiac surgery may improve clinical decision making and research design.… Expand
Preoperative Use of Statins Is Associated with Reduced Early Delirium Rates after Cardiac Surgery
Background:Delirium is an acute deterioration of brain function characterized by fluctuating consciousness and an inability to maintain attention. Use of statins has been shown to decrease morbidity… Expand
Off-pump coronary artery surgery for reducing mortality and morbidity: meta-analysis of randomized and observational studies.
- D. Wijeysundera, W. Beattie, +4 authors R. Cusimano
- Journal of the American College of Cardiology
- 6 September 2005
OBJECTIVES The purpose of this study was to assess the effects of off-pump coronary bypass surgery (OPCAB) on mortality and morbidity. BACKGROUND Despite its potential for reducing morbidity and… Expand
How strong is the evidence for the use of perioperative β blockers in non-cardiac surgery? Systematic review and meta-analysis of randomised controlled trials
Abstract Objective To determine the effect of perioperative β blocker treatment in patients having non-cardiac surgery. Design Systematic review and meta-analysis. Data sources Seven search… Expand
Continuous Intravenous Administration of Ketorolac Reduces Pain and Morphine Consumption After Total Hip or Knee Arthroplasty
The purpose of this study was to determine the analgesic efficacy, opioid-sparing effect, and tolerability of ketorolac administered as an intravenous (IV) bolus followed by a continuous infusion… Expand
Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications: a meta-analysis.
PURPOSE To investigate the effects of alpha(2)-adrenergic agonists on perioperative mortality and cardiovascular complications in adults undergoing surgery. METHODS MEDLINE (1966 to May 2002),… Expand
Recombinant factor VIIa for intractable blood loss after cardiac surgery: a propensity score-matched case-control analysis.
BACKGROUND Cardiac surgery is occasionally complicated by massive blood loss that is refractory to standard hemostatic interventions. Recombinant factor VIIa (rF-VIIa) is being increasingly used as… Expand
Perioperative Myocardial Infarction
More than 230 million major surgeries are performed annually worldwide,1 and this number grows continuously. The 30-day mortality associated with moderate- to high-risk noncardiac surgery in recent… Expand