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Extent of genome-wide linkage disequilibrium in Australian Holstein-Friesian cattle based on a high-density SNP panel
The first comprehensive study on the extent of LD in cattle by analyzing data on 1,546 Holstein-Friesian bulls genotyped for 15,036 SNP markers, and compares LD structure in cattle with public-domain data from both human and mouse is compared. Expand
A Validated Whole-Genome Association Study of Efficient Food Conversion in Cattle
Using whole-genome association, it is found that DNA variants in or near proteins contributing to the background use of energy of the cell were 10 times as common as those affecting appetite and body-mass homeostasis and suggests that certain subsets of micro-RNA are more important for the regulation of this trait. Expand
The sheep genome illuminates biology of the rumen and lipid metabolism
A genome for ewe and ewe Sheep-specific genetic changes underlie differences in lipid metabolism between sheep and other mammals, and may have contributed to the production of wool. Jiang et al.Expand
A microRNA catalog of the developing chicken embryo identified by a deep sequencing approach.
A bioinformatics pipeline was developed to distinguish authentic mature miRNA sequences from other classes of small RNAs and short RNA fragments represented in the sequencing data and detected almost all of the previously known chicken miRNAs and their respective miRNA* sequences. Expand
The bovine lactation genome: insights into the evolution of mammalian milk
The findings support the essentiality of milk to the survival of mammalian neonates and the establishment of milk secretory mechanisms more than 160 million years ago and suggest that this diversity of milk protein composition across species is primarily due to other mechanisms. Expand
Origin, evolution, and biological role of miRNA cluster in DLK-DIO3 genomic region in placental mammals.
Analysis of the mir-379/mir-656 miRNA cluster located within the imprinted DLK-DIO3 region on human chromosome 14 suggests that emergence of this cluster was one of the factors that facilitated evolution of the placental mammals. Expand
Association weight matrix for the genetic dissection of puberty in beef cattle
The association weight matrix results recapitulate the known biology of puberty, captured experimentally validated binding sites, and identified candidate genes and gene–gene interactions for further investigation. Expand
Genome-wide association studies of female reproduction in tropically adapted beef cattle.
Very few of the significant markers for female reproduction traits for the Brahman and Tropical Composite breeds were located in the same chromosomal regions, however, fatness and BW traits as well as serum IGF1 concentration were found to be associated with similar genome regions within and between breeds. Expand
A Primary Assembly of a Bovine Haplotype Block Map Based on a 15,036-Single-Nucleotide Polymorphism Panel Genotyped in Holstein–Friesian Cattle
The results suggest that as many as 75,000–100,000 tag SNPs would be needed to track all important haplotype blocks in the bovine genome, which would require ∼250,000 SNPs in the discovery phase. Expand
Using comparative genomics to reorder the human genome sequence into a virtual sheep genome
It is demonstrated that limited sequencing of BACs combined with positioning on a well assembled genome and integrating locations from other less well assembled genomes can yield extensive, detailed subgene-level maps of mammalian genomes, for which genomic resources are currently limited. Expand