A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise
- W. Aoi, Y. Naito, T. Yoshikawa
- Biology, MedicineGut
- 31 July 2012
Findings suggest that exercise stimulates SPARC secretion from muscle tissues and that SPARC inhibits colon tumorigenesis by increasing apoptosis.
Lifestyle and psychological factors related to irritable bowel syndrome in nursing and medical school students
- Yukiko Okami, Takako Kato, S. Fukudo
- Medicine, PsychologyJournal of gastroenterology
- 24 August 2011
The prevalence of IBS was higher among nursing and medical students, and further interventional studies are needed to improve IBS symptoms.
Muscle-enriched microRNA miR-486 decreases in circulation in response to exercise in young men
- W. Aoi, H. Ichikawa, T. Yoshikawa
- Biology, MedicineFrontiers in Physiology
- 11 April 2013
The reduction in circulating miR-486 may be associated with metabolic changes during exercise and adaptation induced by training and shown a significant negative correlation with VO2max for each subject.
Effect of Brazilian green propolis in patients with type 2 diabetes: A double-blind randomized placebo-controlled study.
- T. Fukuda, M. Fukui, Y. Marunaka
- MedicineBiomedical Reports
- 1 May 2015
A randomized, controlled 8-week trial suggests that Brazilian green propolis prevents patients with type 2 diabetes from developing worse blood uric acid and eGFR and homeostasis model assessment of insulin resistance was not improved by propolis intake.
Oxidative stress and delayed-onset muscle damage after exercise.
- W. Aoi, Y. Naito, T. Yoshikawa
- BiologyFree Radical Biology & Medicine
- 15 August 2004
The microRNA miR-696 regulates PGC-1{alpha} in mouse skeletal muscle in response to physical activity.
- W. Aoi, Y. Naito, T. Yoshikawa
- BiologyAmerican Journal of Physiology. Endocrinology and…
- 1 April 2010
Observations demonstrate that miR-696 is a physical activity-dependent miRNA involved in the translational regulation of PGC-1alpha and skeletal muscle metabolism in mice.
Astaxanthin improves muscle lipid metabolism in exercise via inhibitory effect of oxidative CPT I modification.
- W. Aoi, Y. Naito, T. Yoshikawa
- BiologyBiochemical and Biophysical Research…
- 22 February 2008
Arterial stiffness acutely decreases after whole‐body vibration in humans
- T. Otsuki, Y. Takanami, W. Aoi, Y. Kawai, H. Ichikawa, T. Yoshikawa
- Medicine, BiologyActa Physiologica
- 1 November 2008
This data indicates that whole‐body vibration (WBV)‐induced oscillation mechanically stimulates abdominal and leg arteries and may decrease arterial stiffness, and WBV is feasible in vulnerable and immobilized humans.
Acute exercise increases fibroblast growth factor 21 in metabolic organs and circulation
- Y. Tanimura, W. Aoi, T. Yoshikawa
- Biology, MedicinePhysiological Reports
- 1 June 2016
Results show that acute exercise increased the expression of fibroblast growth factor 21 in skeletal muscle, accompanied by the phosphorylation of Akt in mice, and induced the increase of serum fibro Blast Growth Factor 21 in both humans and mice.
Dietary Intervention with Cooking Instructions and Self-monitoring of the Diet in Free-Living Hypertensive Men
- K. Kitaoka, Junko Nagaoka, A. Higashi
- MedicineClinical and experimental hypertension
- 25 March 2013
In the intervention group, the urinary sodium-to-potassium excretion ratio was significantly improved by focusing on cooking instructions and self-monitoring of the diet.
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