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Intrauterine infection and preterm delivery.
TLDR
Preterm delivery is the chief problem in obstetrics today, accounting for 70 percent of perinatal mortality and nearly half of long-term neurologic morbidity, and the remainder follow the spontaneous onset of labor or rupture. Expand
Diagnosis and management of clinical chorioamnionitis.
TLDR
Clinical research into better methods for diagnosing, treating, and preventing chorioamnionitis is likely to have a substantial impact on short and long-term outcomes in the neonate. Expand
The Alabama Preterm Birth study: polymorphonuclear and mononuclear cell placental infiltrations, other markers of inflammation, and outcomes in 23- to 32-week preterm newborn infants.
TLDR
Polymorphonuclear infiltrations of the free membranes, chorionic plate, and umbilical cord were associated with positive intrauterine cultures and elevated cord blood interleukin-6 and there was an association with systemic inflammatory response syndrome and necrotizing enterocolitis, but not with intraventricular hemorrhage or death, and with decreased respiratory distress syndrome. Expand
The preterm prediction study: significance of vaginal infections. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.
TLDR
The presence of bacterial vaginosis at 28 weeks' gestation is associated with an increased risk of spontaneous preterm birth and detection of Trichomonas vaginalis (by wet mount) or monilia (by potassium hydroxide preparation) had no significant associations with pretermBirth. Expand
The Alabama Preterm Birth Study: umbilical cord blood Ureaplasma urealyticum and Mycoplasma hominis cultures in very preterm newborn infants.
TLDR
Positive cultures are associated with neonatal systemic inflammatory response syndrome and probably bronchopulmonary dysplasia, and cord blood infections are far more common in spontaneous vs indicated preterm deliveries and are strongly associated with markers of acute placental inflammation. Expand
Vaccine prevention of maternal cytomegalovirus infection.
TLDR
CMV glycoprotein B vaccine has the potential to decrease incident cases of maternal and congenital CMV infection and was more likely to remain uninfected during a 42-month period than the placebo group. Expand
Longitudinal Association Between Hormonal Contraceptives and Bacterial Vaginosis in Women of Reproductive Age
TLDR
There was a decreased risk of overall BV prevalence among oral contraceptive users and among those using hormonal injection/implant and less remission occurred among those subjects who had tubal ligation. Expand
Recent advances in the endocrinology of puberty.
TLDR
Researchers of the earlier part of the present century were already more concerned in their definitions with the acquisition of reproductive capacity resulting from the completion of gonadal and accessory sex organ development. Expand
BED REST IN PREGNANCY
TLDR
Bed rest is used extensively to treat a wide variety of pregnancy conditions, at substantial cost but with little proof of effectiveness, and its use during pregnancy should be curtailed unless randomized trials demonstrate improvement in a specific outcome. Expand
Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis.
TLDR
Treatment with metronidazole and erythromycin during the second trimester reduced rates of premature delivery in women with bacterial vaginosis and an increased risk for preterm delivery. Expand
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