• Publications
  • Influence
Herbal medication: potential for adverse interactions with analgesic drugs
  • W. Abebe
  • Medicine, Biology
    Journal of clinical pharmacy and therapeutics
  • 1 December 2002
TLDR
Health‐care professionals should be more aware of the potential adverse interactions between herbal supplements and analgesic drugs, and take appropriate precautionary measures to avoid their possible occurrences.
Enhanced Contractile Responses of Arteries from Diabetic Rats to α1‐Adrenoceptor Stimulation in the Absence and Presence of Extracellular Calcium
TLDR
Enhanced responses of arteries from diabetic rats to α-adrenoceptor agonists are mediated by α1 adrenoceptors, and are largely dependent on the presence of extracellular Ca2+.
Role of taurine in the vasculature: an overview of experimental and human studies.
TLDR
Oral taurine in hypertensive human patients alleviates the symptoms of hypertension and also reverses arterial stiffness and brachial artery reactivity in type 1 diabetic patients, but there is a need to further establish certain aspects of the reported results and also consider addressing unresolved related issues.
Adenosine receptor-mediated relaxation of porcine coronary artery in presence and absence of endothelium.
TLDR
The data suggest that multiple A2-adenosine receptors exist on the smooth muscle and endothelium of porcine coronary artery, mediating relaxation and 5'-uronamide derivatives, such as NECA and CGS-21680.
Role of nitric oxide in adenosine receptor-mediated relaxation of porcine coronary artery.
TLDR
In the present study, using porcine coronary artery rings in vitro, the role of the nitric oxide (NO) pathway in endothelium-dependent vasorelaxant effects of the 5'-uronamide adenosine agonists and 2-[p-(2-carboxyethyl)]phenylethyl-amino-5'-N-ethylcarboxamidoadenosine (CGS-21680) is examined.
Role of Tyrosine Kinases in Norepinephrine‐Induced Contraction of Vascular Smooth Muscle
TLDR
The data indicate that genistein- and tyrphostin-sensitive tyrosine kinases participate in NE-induced contraction of rat aortic smooth muscle, and the enzymes appear to have a greater role in mediating the responses linked to the release of intracellular calcium.
An Overview of Ethiopian Traditional Medicinal Plants Used for Cancer Treatment
TLDR
An overview of the literature reporting the use of Ethiopian traditional medicinal plants for cancer treatment is provided, finding that a large majority of the plants reported were used for treating human cancer, with most of them belonging to different plant families.
Mechanisms of load dependency of myocardial ischemia reperfusion injury.
TLDR
Mechanisms of cardiac ischemia reperfusion injury are described followed by a discussion of how pressure/mechanical stress modulates endogenous cardiotoxic and cardioprotective mechanisms to ultimately exacerbate ischemic reperfusions injury.
Mitochondrial complex I and NAD(P)H oxidase are major sources of exacerbated oxidative stress in pressure-overloaded ischemic-reperfused hearts
TLDR
Increased oxidative and nitrosative stress, coupled with lack of augmented SOD and catalase activities, contributes importantly to the exacerbating impact of pressure overload on MPT pore opening and cell death in ischemic-reperfused hearts.
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