W. A. Bickmore

Sort by:

The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells.

Sean D Boyle, Stefanie Gilchrist, Janice Bridger, Nathalie Mahy, Justine A. Ellis, W. A. Bickmore
Human molecular genetics
2001

To fully understand genome function, the linear genome map must be integrated with a spatial map of chromosomes in the nucleus. Distinct nuclear addresses for a few human chromosomes have been… (More)

A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis.

Ke Ma, James Inglis, +7 authors K. Taylor
Cell
1993

We have previously mapped the human azoospermia factor to a deletion in Y chromosome interval 6 (subinterval XII-XIV). We now report the isolation and characterization of a gene family located within… (More)

The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo.

Jean Armstrong, Katherine Pritchard-Jones, W. A. Bickmore, N. D. Hastie, Judith Bard
Mechanisms of development
1993

In the developing mouse, the Wilms' tumour gene, WT1, is first expressed in the intermediate mesenchyme lateral to the coelomic cavity (13 somite, early 9 dpc embryo). A few hours later, it is… (More)

Re-modelling of nuclear architecture in quiescent and senescent human fibroblasts

Janice Bridger, Sean D Boyle, Ian R. Kill, W. A. Bickmore
Current Biology
2000

Spatial organisation of the genome within the nucleus can play a role in maintaining the expressed or silent state of some genes [1]. There are distinct addresses for specific chromosomes, which have… (More)

The Nuclear Protein Database (NPD): sub-nuclear localisation and functional annotation of the nuclear proteome

Graham Dellaire, R. Farrall, W. A. Bickmore
Nucleic Acids Research
2003

The Nuclear Protein Database (NPD) is a curated database that contains information on more than 1300 vertebrate proteins that are thought, or are known, to localise to the cell nucleus. Each entry is… (More)

Chromosome bands--flavours to savour.

J M Craig, W. A. Bickmore
BioEssays : news and reviews in molecular…
1993

The mammalian chromosome is longitudinally heterogeneous in structure and function and this is the basis for the specific banding patterns produced by various chromosome staining techniques. The two… (More)

Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes.

Teresa McDowell, Rachel Gibbons, +10 authors Douglas R Higgs
Proceedings of the National Academy of Sciences…
1999

ATRX is a member of the SNF2 family of helicase/ATPases that is thought to regulate gene expression via an effect on chromatin structure and/or function. Mutations in the hATRX gene cause severe… (More)

Factors affecting the timing and imprinting of replication on a mammalian chromosome.

W. A. Bickmore, Andrew D. Carothers
Journal of cell science
1995

Fluorescence in situ hybridisation has been used to follow replication of the short arm of human chromosome 11 using chromosome anomalies to distinguish the maternally-and paternally-derived… (More)

Large-scale identification of mammalian proteins localized to nuclear sub-compartments.

Hamish Sutherland, G. K. Mumford, +5 authors W. A. Bickmore
Human molecular genetics
2001

Many nuclear components participating in related pathways appear concentrated in specific areas of the mammalian nucleus. The importance of this organization is attested to by the dysfunction that… (More)

HuCHRAC, a human ISWI chromatin remodelling complex contains hACF1 and two novel histone-fold proteins.

Raymond A. Poot, Graham Dellaire, +5 authors Patrick Daniel Varga-Weisz
The EMBO journal
2000

Chromatin remodelling complexes containing the nucleosome-dependent ATPase ISWI were first isolated from Drosophila embryos (NURF, CHRAC and ACF). ISWI was the only common component reported in these… (More)

Filter Results:

Publication Year

Publication Type

Co-author

Journals and Conferences