W. Travis Goldsmith

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BACKGROUND Involuntary cough is a classic symptom of many respiratory diseases. The act of coughing serves a variety of functions such as clearing the airways in response to respiratory irritants or aspiration of foreign materials. It has been pointed out that a cough results in substantial stresses on the body which makes voluntary cough a useful tool in(More)
Cough is considered an early sign of many respiratory diseases. Recently, there has been increased interest in measuring, analyzing, and characterizing the acoustical properties of a cough. In most cases the main focus of those studies was to distinguish between involuntary coughs and ambient sounds over a specified time period. The objective of this study(More)
Measurement of partial expiratory flow-volume curves has become an important technique in diagnosing lung disease, particularly in children and in the elderly. The objective of this study was to investigate the feasibility of predicting abnormal spirometry using the partial flow-volume curve generated during a voluntary cough. Here, abnormal spirometry is(More)
INTRODUCTION Oil spill cleanup workers come into contact with numerous potentially hazardous chemicals derived from the oil spills, as well as chemicals applied for mitigation of the spill, including oil dispersants. In response to the Deepwater Horizon Macondo well oil spill in the Gulf of Mexico in 2010, a record volume of the oil dispersant, COREXIT(More)
BACKGROUND To prepare for a possible influenza pandemic, a better understanding of the potential for the airborne transmission of influenza from person to person is needed. OBJECTIVES The objective of this study was to directly compare the generation of aerosol particles containing viable influenza virus during coughs and exhalations. METHODS Sixty-one(More)
Inhalation of diacetyl, a butter flavoring, causes airway responses potentially mediated by sensory nerves. This study examines diacetyl-induced changes in sensory nerves of tracheal epithelium. Rats (n = 6/group) inhaled 0-, 25-, 249-, or 346-ppm diacetyl for 6 hr. Tracheas and vagal ganglia were removed 1-day postexposure and labeled for substance P (SP)(More)
Most murine models of fungal exposure are based on the delivery of uncharacterized extracts or liquid conidia suspensions using aspiration or intranasal approaches. Studies that model exposure to dry fungal aerosols using whole body inhalation have only recently been described. In this study, we aimed to characterize pulmonary immune responses following(More)
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