W. Storkebaum

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From plasma of essential hypertensives and normotensives several fractions were obtained after: (1) removing proteins with a relative molecular mass greater than 6,000-8,000, and (2) chromatography on a Biogel P4 or Biogel P2 column. The eluate was separated into 3-4 fractions. These fractions were concentrated to a small volume of 0.5 ml and were injected(More)
In 56 spontaneously hypertensive rats of the Muenster strain, either parabiosis or cross circulation was performed with normotensive Wistar Kyoto rats. Crossed circulation was made through the common carotid arteries and external jugular veins using a peristaltic pump. In parabiosis and in cross-circulation experiments, hypertension was transmitted from(More)
The effect of fractions of plasma from essential hypertensive (n = 27) and normotensive subjects (n = 26) on the tension of aortic strips (n = 27) from normotensive rats was examined. The fractions obtained from hypertensive patients had been shown to increase blood pressure, when injected intravenously in a normotensive rat. In aortic strips the(More)
The effects of plasma fractions from essential hypertensives (n = 17) and normotensives (n = 17) on Ca2+ transport in permeabilised human neutrophils were studied using an ion-selective electrode. The plasma fractions were obtained by gel filtration and contained substances with a molecular weight in the range of 1000-1500 Da. When isolated from essential(More)
1. Isolated perfused rat kidneys were used to study the effects of plasma fractions obtained by gel filtration from essential hypertensive patients (n = 40) and from normotensive subjects (n = 36) on resistance vessels. Perfusion pressure was recorded at a constant flow. 2. Plasma fractions were obtained by gel filtration and contained substances with a(More)
Using a polyclonal antibody raised in rabbits against the highly purified di-isopropyl-fluorophosphate fluorohydrolase (DFPase, E.C. 3.8.2.1) of hog kidney, DFPase-immunoreactivity could be demonstrated by the unlabelled antibody peroxidase-antiperoxidase immunohistochemical method in the hog kidney in the brush border of epithelial cells in the proximal(More)
1. The effects of plasma fractions from essential hypertensive subjects (n = 14) and normotensive subjects (n = 14) on Ca2+ transport in permeabilized human neutrophils was studied using an ion-selective electrode. 2. Plasma fractions were obtained by gel filtration and contained substances with a molecular mass in the range 1000-1500 daltons. This fraction(More)
Different vascular models of normotensive Wistar rats, including aortic strips, isolated perfused mesentery and isolated perfused kidney, were used to study hemodynamic effects of plasma fractions obtained by gel filtration from the blood of essential hypertensive and normotensive subjects. Plasma fractions from essential hypertensives studied had been(More)
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