The levels of total and free tryptophan were determined in the plasma of 34 endogenous depressives, 20 neurotic depressives and 25 healthy volunteers. Whilst the levels of total tryptophan were not different in the three groups, the level of free tryptophan was reduced in both endogenous and neurotic depressives.
Polygraphic examinations were made during the day on 6 normal subjects. Simultaneous evaluation of EEG, EOG and EMG was carried out over 30 sec epochs. The data thus obtained were correlated with the various types of behaviour and activities during the day and then interpreted. Six conditions could be defined corresponding to different waking stages. The… (More)