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OBJECTIVE Lymphoproliferative lesions of the ocular adnexa were analyzed to examine (1) the suitability of the Revised European-American Lymphoma (REAL) classification for the subtyping of the lymphomas in these sites; (2) the predictive value of the REAL classification for the evolution of these tumors; and (3) the frequency and prognostic impact of tumor(More)
Advanced selection technologies have been developed and continually optimized to improve traits of agricultural importance; however, these methods have been primarily applied without knowledge of underlying biological changes that may be induced by selection. This study aims to characterize the biological basis of differences between chickens with low and(More)
The mechanisms of erythrocyte disposal by the trabecular meshwork in the human eye have not been extensively studied by electron microscopy. At the present time there is one short report on the ultrastructural changes induced by post-traumatic recurrent hyphaemas in two elderly patients. In both patients, Yamashita and Rosen ( I965) observed infiltration of(More)
BACKGROUND The "true" prevalence and clinical attributes of exfoliation glaucoma remain controversial. The authors studied these characteristics in glaucoma patients requiring trabeculectomy. METHODS One hundred consecutive patients undergoing trabeculectomy for open-angle glaucoma were investigated by clinical examination (biomicroscopy and gonioscopy)(More)
This paper presents a new method for the design of sharp linear phase FIR filters using the frequency-response masking (FRM) technique. The method is based on a weighted least square (WLS) approach, and the design problem is solved iteratively. The original least square (LS) problem is decomposed into two LS problems, each of which can be solved(More)
OBJECTIVE Lymphomas of the eye and its adnexa are frequently of B lineage. This study aims to characterize the clinical and histopathologic features of the rare non-B-cell non-Hodgkin lymphomas (NHL) of these locations. DESIGN Retrospective, noncomparative case series. PARTICIPANTS Seven cases of T- and T/NK-cell lymphomas involving the ocular and(More)
PURPOSE To support the hypothesis that Acanthamoeba is not a unique cause of amebic keratitis, we report a case of amebic keratitis in which viable Acanthamoeba could not be isolated from corneal tissue. Vahlkampfia and Hartmannella, two other genera of free-living ameba, were isolated, however, using prolonged culture. METHODS A 24-year-old wearer of(More)
AIMS/BACKGROUND Metastatic disease in patients with ocular melanoma is resistant to chemotherapy. One of the main mechanisms of modulating multidrug resistance is the expression of the multidrug resistance gene 1 (MDR1) product (p-glycoprotein) by tumour cells. The purpose of this study was to evaluate the frequency of expression of the MDR1 gene in ocular(More)
We have developed a model system for studying proliferative retinopathy in vitro using bovine retinal explants cultured in collagen gels. Cellular outgrowth from retinal explants occurred after 7 days as single cells from peripapillary explants or as cell sheets and tubular outgrowths from peripheral retinal explants. Single cell outgrowths were shown(More)
In a transmission electron microscopic investigation of the endothelium lining Schlemm's canal subjected to graded levels of intraocular pressure (0 to 50 mm Hg for one hour), there was an increase in the number of vacuolar structures with the increase in pressure (range, 8 to 30 mm Hg). At 0 mm Hg, giant vacuoles were absent, while at 50 mm Hg their(More)