W R Holloway

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Three standard CNS stimulants were tested for effect on juvenile play soliciting in prepubertal male rats (n = 120). Three dosages of each stimulant were compared with a saline control. Soliciting behavior was isolated and magnified by a novel method incorporating pretest social deprivation and social response to a standard nonplayful social stimulus(More)
Lactating female rats reared litters consisting of 4, 8 or 12 pups. At weaning (21 days) females were removed from their maternity cages and exposed to a 1-min ether stress followed by heart puncture. The animals were then isolated and 14 min after the termination of ether stress blood was collected by decapitation. Plasma prolactin and corticosterone were(More)
The behavioral responses of 1- and 10-day-old rats to caffeine, a central nervous system stimulant, were determined using several behaviors readily exhibited by the neonatal rat. In pups of both ages activity as well as attachment latencies in the on-nipple suckling test increased, while weight gain and attachment frequencies in on-mother and on-nipple(More)
Lactating rats were given distilled water or distilled water containing 0.067% lead chloride (500 ppm lead) as their sole source of drinking fluid from Days 1-21 of lactation. Activity, social investigation and rough and tumble play fighting behaviors of the offspring were observed on Day 26 and activity and play solicitation behaviors on Day 36. Although(More)
The purpose of this paper was to present a quantitative analysis of parturition in the laboratory rat. In addition, the effects of parity were also investigated. Gestational length was 22-23 days (day sperm found was Day 1) in 95% of the pregnancies. The average length of parturition was 97.3 min. The mean litter size was 10.84 pups and the average weight(More)
The social play behavior of juvenile rats was originally described nearly a century ago, but research methods have only recently included the controlled laboratory investigation of psychobiological variables. This review covers the experimental literature of social play or play fighting behavior in juvenile laboratory rats reported during the last decade.(More)
Play fighting, social investigation, and locomotor activity of prepubescent male laboratory rats were observed 20 min following administration of scopolamine hydrobromide. Play fighting was inhibited by an intraperitoneal dosage of 0.3 mg/kg and was effectively blocked at all dosages greater than 0.5 mg/kg; activity and social investigatory behavior were(More)
Persistence of social attention by male and female laboratory rats was examined following exposure to novel conspecifics. In experiment I we compared performance of castrate female controls. Testosterone significantly prolonged mean social investigation time. Castrate females treated with a 10-day regimen of testosterone propionate to that of intact males(More)