W Pakszys

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The results of substitutive treatment of Parkinson's disease with L-dopa were assessed using a special chart for periodical examinations. This chart contains, among others, a 100-point scoring scale of parkinsonian disability which makes possible objective comparison of the condition of patients after various duration of treatment. The obtained results were(More)
The authors tried to apply ultrasound stimulation of the lymphatic system in patients with multiple sclerosis. This trial was undertaken in view of reports of German authors on favourable results of this therapeutic method. The treated group included 24 patients aged 20--54 years with steady or slowly progressive course of this disease in whom spastic(More)
Bioavailability of Phenytoin "Polfa" tablets was studied in comparison with Epanutin "Parke-Davis" capsules. It was found that the relative degree of bioavailability of Phenytoin in relation to Epanutin as a standard is 70,7 +/- 6,3% (SD). The cause of worse bioavailability of Phenytoin "Polfa" are differences in pharmaceutical forms of both preparations.(More)
Clinical and electroencephalographic investigations were performed and the diphenylhydantoin level was determined in the serum in a homogenous group of 32 young males aged 20-22 years staying in hospital. The spectrophotometric determination of the drug was found to be useful. The effect of therapeutic DPH level on regression of abnormal EEG tracings was(More)
Serum DPH level was determined in previously untreated epileptics who were receiving one dose of 300 mg of DPH daily (Phenytoin--Polfa) during 21 days. The DPH level was determined on the 1st, 10th and 21st days after starting treatment. The obtained results show significant individual differences in absorption of DPH. In 5 patients lower therapeutic range(More)
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