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Circulating miRNAs (microRNAs) are emerging as promising biomarkers for several pathological conditions, and the aim of this study was to investigate the feasibility of using serum miRNAs as biomarkers for liver pathologies. Real-time qPCR (quantitative PCR)-based TaqMan MicroRNA arrays were first employed to profile miRNAs in serum pools from patients with(More)
Cultivation conditions of cellulases production by Aspergillus niger HQ-1 in solid-state fermentation (SSF) were optimized. Furthermore, partial enzymatic characterization of the crude cellulases on hydrolyzing chitosan was studied. The moisture content, cultivation temperature, and initial culture pH were identified by Plackett-Burman design (PBD) as the(More)
Cysteinyl leukotrienes are potent pro-inflammatory mediators. Cysteinyl leukotriene receptor 1 is one of the two cysteinyl leukotriene receptors cloned. We recently reported that cysteinyl leukotriene receptor 1 antagonists protected against cerebral ischemic injury, and an inducible expression of cysteinyl leukotriene receptor 1 was found in neuron- and(More)
Cysteinyl leukotrienes (CysLTs), potent inflammatory mediators, are released from ischemic brain, and may regulate ischemic injury through activating CysLT1 and CysLT2 receptors. The CysLT1 receptor is closely associated with ischemic injury and post-ischemic repair; however, the CysLT2 receptor-mediated responses remain unknown. Here, we investigated the(More)
G protein-coupled receptor 17 (GPR17), the new P2Y-like receptor, is phylogenetically related to the P2Y and cysteinyl leukotriene receptors, and responds to both uracil nucleotides and cysteinyl leukotrienes. GPR17 has been proposed to be a damage sensor in ischemic stroke; however, its role in brain inflammation needs further detailed investigation. Here,(More)
The sensory projections from the whiskers of mice and other rodents synapse somatotopically in 3 subnuclei in the brainstem trigeminal complex, in the ventrobasal complex of the thalamus and in the somatosensory cortex. Deafferentation of the whiskers in adult animals results in qualitative and quantitative changes in activities of the metabolic enzymes in(More)
In next generation heterogeneous wireless networks, a user with a multi-mode terminal may have different bearer services using different access technologies. Various approaches can be applied to improve user QoS, such as bandwidth degradation for real-time services, integration of real-time and data traffic, and overflow traffic in overlay networks. In this(More)
In this paper we describe the use of a standard game console joystick, namely the Nintendo WIIMOTE, for an active real-time 3D marker tracking. We show the ease of applicability of inexpensive and standard game controllers for 3D object tracking, e. g to track an infrared source in 3D space. Recovering the 3D information using stereo vision is still one of(More)
Cysteinyl leukotrienes (CysLTs) induce inflammatory responses by activating their receptors, CysLT1R and CysLT2R. We have reported that CysLT2R is involved in neuronal injury, astrocytosis, and microgliosis, and that intracerebroventricular (i.c.v.) injection of the selective CysLT2R antagonist HAMI 3379 protects against acute brain injury after focal(More)